(Q48295224)

10 February 2018

title

Genomic characterization of the RUNX2 gene of Fugu rubripes. (English)

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10 February 2018

author name string

Jan Henrik Eggers

1

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10 February 2018

Michael Stock

2

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10 February 2018

Manfred Fliegauf

3

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10 February 2018

Birgitta Vonderstrass

4

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10 February 2018

Florian Otto

5

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10 February 2018

language of work or name

English

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publication date

1 May 2002

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10 February 2018

published in

Gene

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10 February 2018

volume

291

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10 February 2018

page(s)

159-167

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10 February 2018

issue

1-2

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10 February 2018

Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes

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Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli

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Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome

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Runt and Lozenge function in Drosophila development

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A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development

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Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning

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Regulation of chondrocyte differentiation by Cbfa1

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

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PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

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Two domains unique to osteoblast-specific transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta

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Potential roles for RUNX1 and its orthologs in determining hematopoietic cell fate

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

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Identifiers

DOI

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10 February 2018

PubMed ID

12095689

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10 February 2018