Wikidata

(Q4835575)

English

BH3 interacting domain death agonist

mammalian protein found in Homo sapiens

  • Human BID coding sequence
  • BID
  • p22 BID
  • BH3-interacting domain death agonist
  • desmocollin type 4
  • apoptic death agonist
  • BID isoform L(2)
  • BH3 interacting domain death agonist Si6 isoform
  • BID isoform ES(1b)
  • BID isoform Si6
In more languages

Statements

molecular function
protein binding
determination method
IPI
21 references
retrieved
8 April 2019
stated in
PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer.
GOA
curator
UniProt
UniProt protein ID
P55957
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangements
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
BID-induced structural changes in BAK promote apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of Bid-induced apoptosis by Bcl-2. tBid insertion, Bax translocation, and Bax/Bak oligomerization suppressed
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
The DNA-binding domain mediates both nuclear and cytosolic functions of p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
A stapled BID BH3 helix directly binds and activates BAX
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
retrieved
8 April 2019
stated in
Heterodimerization of BAK and MCL-1 activated by detergent micelles
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P55957
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE BID 204493 at fs.png
732 × 530; 10 KB
0 references

Identifiers

 
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