(Q48392880)

English

Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors.

scientific article published in January 1993

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scholarly article

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors. (English)

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

1 reference

based on heuristic

inferred from title

neurotransmitter

1 reference

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author name string

J E Leysen

1

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

P M Janssen

2

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

A Schotte

3

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

W H Luyten

4

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

A A Megens

5

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

publication date

1 January 1993

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

Psychopharmacology

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

112

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

S40-54

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

1 Suppl

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

https://scigraph.springernature.com/pub.10.1007/bf02245006

0 references

Neuroleptic responsivity of negative and positive symptoms in schizophrenia.

1 reference

https://api.crossref.org/works/10.1007%2FBF02245006

21 January 2018

New Antipsychotics: Classification, Efficacy, and Adverse Effects

1 reference

https://api.crossref.org/works/10.1007%2FBF02245006

21 January 2018

Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine

1 reference

https://api.crossref.org/works/10.1007%2FBF02245006

21 January 2018

An anatomy of schizophrenia?

1 reference

https://api.crossref.org/works/10.1007%2FBF02245006

21 January 2018

Molecular biology of the dopamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

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Effect of drugs influencing central serotonergic mechanisms on haloperidol-induced catalepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melperone in the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic effect and safety of increasing doses of risperidone (R 64766) in psychotic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pilot Clinical Investigation of Risperidone in the Treatment of Psychotic Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha 1-Adrenoceptors in the mammalian brain: similar pharmacology but different distribution in rodents and primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double-blind comparative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ratios of serotonin2 and dopamine2 affinities differentiate atypical and typical antipsychotic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A retrospective evaluation of pipamperone (Dipiperon) in the treatment of behavioural deviations in severely mentally handicapped

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amperozide: a new pharmacological approach in the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural determinants of sigma receptor affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of tiospirone vs. haloperidol and thioridazine in a double-blind, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gaps and peculiarities in 5-HT2 receptor studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pipamperone (Dipiperon, R3345) in troublesome mental retardates: a double-blind placebo controlled cross-over study with long-term follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A detailed mapping of dopamine D-2 receptors in rat central nervous system by autoradiography with [125I]iodosulpride

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antischizophrenic drugs: affinity for muscarinic cholinergic receptor sites in the brain predicts extrapyramidal effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double blind comparative study of remoxipride and haloperidol in acute schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remoxipride. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The purely neuroleptic effects and its relation to the "neuroleptic threshold"

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antagonistic effect of cyproheptadine on neuroleptic-induced catalepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative autoradiographic localization of alpha 2-antagonist binding sites in rat brain using [3H]idazoxan.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo receptor binding and effects on monoamine turnover in rat brain regions of the novel antipsychotics risperidone and ocaperidone

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profiles of clinical efficacy and pharmacological action of zotepine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Additional studies on side effects of melperone in long-term therapy for 1-20 years in psychiatric patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine: neuroleptic-induced EPS and tardive dyskinesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral activity of rats measured by a new method based on the piezo-electric principle

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between the argininyl moieties of neurotensin and the catechol protons of dopamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remoxipride, a novel atypical neuroleptic, in the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The third dopamine receptor (D3) as a novel target for antipsychotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT2 receptor blockade by ICI 169,369 and other 5-HT2 antagonists modulates the effects of D-2 dopamine receptor blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroleptic affinities for human brain receptors and their use in predicting adverse effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence and interpretation of psychomotor parkinsonism in megaphen or largactil prolonged therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sleep disorders in patients with severe mental depression: Double-blind placebo-controlled evaluation of the value of pipamperone (Dipiperon®)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An open label trial of raclopride in acute schizophrenia. Confirmation of D2-dopamine receptor occupancy by PET

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical profile of risperidone, a new antipsychotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological study of [2-chloro-11-(2-dimethylaminoethoxy) dibenzo[b,f]thiepine] (zotepine), a new neuroleptic drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple human D5 dopamine receptor genes: a functional receptor and two pseudogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonergic component of neuroleptic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of antipsychotic drugs on serotonin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral disinhibition and depression in amphetaminized rats: a comparison of risperidone, ocaperidone and haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of serotonergic agents on haloperidol-induced catalepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A proposal for the classification of sigma binding sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effector coupling mechanisms of the cloned 5-HT1A receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tiaspirone in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metoclopramide and sulpiride as selective blocking agents of pre- and postsynaptic dopamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT1A receptor responsivity in anxiety disorders and depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the effects of haloperidol, remoxipride and raclopride on "pre"- and postsynaptic dopamine receptors in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sensitivity of two dopaminergic structures in rat brain to haloperidol and to clozapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nucleus accumbens–possible site of antipsychotic action of neuroleptic drugs?

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do functional relationships exist between 5-HT1A and 5-HT2 receptors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amperozide: the pharmacological profile of a novel antipsychotic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential neuroleptic agents. 4. Chemistry, behavioral pharmacology, and inhibition of [3H]spiperone binding of 3,5-disubstituted N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxysalicylamides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-HT2 antagonist ritanserin in neuroleptic-induced parkinsonism: a double-blind comparison with orphenadrine and placebo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel antipsychotic drugs share high affinity for sigma receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of the new antipsychotic risperidone on large and small motor movements in rats: a comparison with haloperidol

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remoxipride, a new selective D2 antagonist, and haloperidol in cebus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pipamperone (Dipiperon) in the treatment of behaviour disorders. A large-scale multicentre evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A microcomputer program for fitting enzyme inhibition rate equations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain dopamine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of amperozide in schizophrenia. An open study of a potent 5-HT2 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pipamperone (Dipiperon), a useful sedative neuroleptic drug in troublesome chronic psychotic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7530377

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF02245006

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/7530377

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