(Q48567039)

12 February 2018

title

Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. (English)

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12 February 2018

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3

Pier Paolo Pandolfi

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12 February 2018

5

Terry Van Dyke

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12 February 2018

author name string

Andrew Xiao

series ordinal

1

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12 February 2018

Hua Wu

series ordinal

2

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12 February 2018

David N Louis

series ordinal

4

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12 February 2018

publication date

1 March 2002

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12 February 2018

published in

Cancer Cell

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12 February 2018

volume

1

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12 February 2018

page(s)

157-168

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12 February 2018

issue

2

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12 February 2018

GFAP promoter directs astrocyte-specific expression in transgenic mice.

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PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

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An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

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Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression

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Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

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Cell signaling by receptor tyrosine kinases

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High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

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Development and malignant progression of astrocytomas in GFAP-v-src transgenic mice

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Identifiers

DOI

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12 February 2018

PubMed ID

12086874

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12 February 2018