(Q48572020)

English

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12077187

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Gwenn A Garden

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Randell T Libby

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Ying-Hui Fu

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Yoshito Kinoshita

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Jing Huang

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Daniel E Possin

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Annette C Smith

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Refugio A Martinez

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Gabriel C Fine

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Sara K Grote

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Carol B Ware

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

David D Einum

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Richard S Morrison

13

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Louis J Ptacek

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Bryce L Sopher

15

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Albert R La Spada

16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 June 2002

1 reference

Europe PubMed Central

12 February 2018

http://europepmc.org/abstract/MED/12077187

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

22

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

4897-4905

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine repeats and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression analysis of ataxin-7 mRNA and protein in human brain: evidence for a widespread distribution and focal protein accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB-binding protein sequestration by expanded polyglutamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamine disease and neuronal cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurological abnormalities in a knock-in mouse model of Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ataxin-7 expression analysis in controls and spinocerebellar ataxia type 7 patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Qs in the nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant protein in Huntington disease is resistant to proteolysis in affected brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF as an anterophin; a novel neurotrophic relationship between brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary olivopontocerebellar atrophy with retinal degeneration. Report of a family through six generations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autosomal dominant cerebellar ataxia with pigmentary macular dystrophy. A clinical and genetic study of eight families.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntington's disease and dentatorubral-pallidoluysian atrophy: proteins, pathogenesis and pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of the caspases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein fate in neurodegenerative proteinopathies: polyglutamine diseases join the (mis)fold

1 reference

https://pubmed.ncbi.nlm.nih.gov/12077187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-12-04897.2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757746&resulttype=core&format=json

12 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q48572020&oldid=1483125137"