(Q48637762)

13 February 2018

title

Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon. (English)

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13 February 2018

author name string

Rouillé Y

1

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13 February 2018

Bianchi M

2

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13 February 2018

Irminger JC

3

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13 February 2018

Halban PA

4

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13 February 2018

language of work or name

English

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publication date

1 August 1997

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13 February 2018

number of pages

5

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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13 February 2018

volume

413

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13 February 2018

page(s)

119-123

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13 February 2018

issue

1

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13 February 2018

Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases.

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The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

21 January 2018

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Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

21 January 2018

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PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues

21 January 2018

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Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3

21 January 2018

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Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells

21 January 2018

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Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms. Cleavage at a single arginine residue

21 January 2018

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Characterization of the endopeptidase PC2 activity towards secretogranin II in stably transfected PC12 cells

21 January 2018

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Specificity of prohormone convertase endoproteolysis of progastrin in AtT-20 cells

21 January 2018

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Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin

21 January 2018

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Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA.

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Identical mRNA for preproglucagon in pancreas and gut.

21 January 2018

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Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

21 January 2018

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21 January 2018

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Conversion of proglucagon in pancreatic alpha cells: the major endproducts are glucagon and a single peptide, the major proglucagon fragment, that contains two glucagon-like sequences

21 January 2018

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Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells

21 January 2018

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Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide

21 January 2018

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21 January 2018

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The role of prohormone convertases PC1 (PC3) and PC2 in the cell-specific processing of proglucagon

21 January 2018

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Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro.

21 January 2018

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Hamster preproglucagon contains the sequence of glucagon and two related peptides.

21 January 2018

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Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

21 January 2018

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Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

21 January 2018

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Hormonal induction of secretory granules in a pituitary tumor cell line

21 January 2018

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21 January 2018

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7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity

21 January 2018

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Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

21 January 2018

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Pro-thyrotropin-releasing hormone processing by recombinant PC1

21 January 2018

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Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2

7 January 2021

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Proneuropeptide Y processing in large dense-core vesicles: manipulation of prohormone convertase expression in sympathetic neurons using adenoviruses

7 January 2021

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Molecular forms of glucagon-like peptides in man

7 January 2021

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Distribution of oxyntomodulin and glucagon in the gastrointestinal tract and the plasma of the rat

7 January 2021

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Distribution of the Kexin family proteases in pancreatic islets: PACE4C is specifically expressed in B cells of pancreatic islets

7 January 2021

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Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus

7 January 2021

1 reference

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10.1016/S0014-5793(97)00892-2

7 January 2021

Identifiers

DOI

1 reference

13 February 2018

PubMed ID

9287128

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13 February 2018