(Q48657475)

14 February 2018

title

Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis. (English)

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14 February 2018

author name string

Gomez-Manzano C

1

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14 February 2018

Fueyo J

2

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14 February 2018

Kyritsis AP

3

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14 February 2018

McDonnell TJ

4

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14 February 2018

Steck PA

5

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14 February 2018

Levin VA

6

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14 February 2018

Yung WK

7

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14 February 2018

language of work or name

English

0 references

publication date

1 July 1997

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14 February 2018

Journal of the National Cancer Institute

number of pages

9

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based on heuristic

inferred from page(s)

published in

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14 February 2018

volume

89

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14 February 2018

page(s)

1036-1044

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14 February 2018

issue

14

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14 February 2018

Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies

cites work

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

p53 function and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Apoptosis in cancer therapy: crossing the threshold

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Genetic determinants of p53-induced apoptosis and growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Mitotic recombination of chromosome 17 in astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Clonal expansion of p53 mutant cells is associated with brain tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

p53 protein accumulation and gene mutations in human glioma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Expression of epidermal growth factor receptor and associated glycoprotein on cultured human brain tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Features of apoptotic cells measured by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Analysis of glioma cell lines for amplification and overexpression of MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Single cell monitoring of growth arrest and morphological changes induced by transfer of wild-type p53 alleles to glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

A p53-dependent mouse spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

Cells en route to apoptosis are characterized by the upregulation of c-fos, c-myc, c-jun, cdc2, and RB phosphorylation, resembling events of early cell-cycle traverse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNCI%2F89.14.1036

21 January 2018

Identifiers

DOI

10.1093/JNCI/89.14.1036

1 reference

14 February 2018

PubMed ID

9230885

1 reference

14 February 2018