(Q48892500)

16 February 2018

title

Bcl-xL does not inhibit the function of Apaf-1. (English)

1 reference

16 February 2018

author

Ruth Kluck

3

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16 February 2018

author name string

Newmeyer DD

1

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16 February 2018

Bossy-Wetzel E

2

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16 February 2018

Wolf BB

4

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16 February 2018

Beere HM

5

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16 February 2018

Green DR

6

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16 February 2018

publication date

1 April 2000

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16 February 2018

Cell Death & Differentiation

published in

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16 February 2018

volume

7

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16 February 2018

page(s)

402-407

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16 February 2018

issue

4

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16 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4400665

exact match

0 references

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

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Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

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21 January 2018

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Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Bcl-x(L) forms an ion channel in synthetic lipid membranes.

21 January 2018

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

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Checkpoints of dueling dimers foil death wishes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400665

inferred from DOI database lookup

7 January 2021

based on heuristic

Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400665

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.CDD.4400665

1 reference

16 February 2018

PubMed ID

10773825

1 reference

16 February 2018