(Q48974769)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Alpha-1-antichymotrypsin promotes beta-sheet amyloid plaque deposition in a transgenic mouse model of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

0 references

L N Nilsson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

K R Bales

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

G DiCarlo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

M N Gordon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

D Morgan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

S M Paul

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

H Potter

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

language of work or name

English

0 references

publication date

1 March 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

1444-1451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

4 November 2019

cites work

1 reference

12 December 2020

Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution.

1 reference

12 December 2020

Accelerated evolution in the reactive centre regions of serine protease inhibitors.

1 reference

12 December 2020

The Involvement of Proteases, Protease Inhibitors, and an Acute Phase Response in Alzheimer's Disease a

1 reference

12 December 2020

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

1 reference

12 December 2020

Inflammation and Alzheimer's disease

1 reference

12 December 2020

Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.

1 reference

12 December 2020

Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice

1 reference

12 December 2020

Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin.

1 reference

12 December 2020

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1 reference

12 December 2020

Identification of a cis-acting positive regulatory element of the glial fibrillary acidic protein gene

1 reference

12 December 2020

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

1 reference

12 December 2020

Alzheimer's peptide Abeta1-42 binds to two beta-sheets of alpha1-antichymotrypsin and transforms it from inhibitor to substrate.

1 reference

12 December 2020

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

1 reference

12 December 2020

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by A beta-related peptides

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

12 December 2020

Association of an interleukin 1 alpha polymorphism with Alzheimer's disease

1 reference

12 December 2020

A specific structural interaction of Alzheimer's peptide A beta 1-42 with alpha 1-antichymotrypsin.

1 reference

12 December 2020

The prionoses and other conformational disorders

1 reference

12 December 2020

Molecular studies define the primary structure of alpha1-antichymotrypsin (ACT) protease inhibitor in Alzheimer's disease brains. Comparison of act in hippocampus and liver

1 reference

12 December 2020

An RNA polymerase II promoter containing sequences upstream and downstream from the RNA startpoint that direct initiation of transcription from the same site

1 reference

12 December 2020

A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia.

1 reference

12 December 2020

Developmental expression of alpha 1-antichymotrypsin in brain may be related to astrogliosis.

1 reference

12 December 2020

Expression of the Alzheimer amyloid-promoting factor antichymotrypsin is induced in human astrocytes by IL-1.

1 reference

12 December 2020

Association of alpha1-antichymotrypsin polymorphism with cerebral amyloid angiopathy.

1 reference

12 December 2020

Quantitative analysis of senile plaques in Alzheimer disease: observation of log-normal size distribution and molecular epidemiology of differences associated with apolipoprotein E genotype and trisomy 21 (Down syndrome).

1 reference

12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

12 December 2020

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

12 December 2020

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

1 reference

12 December 2020

Association of interleukin-1 gene polymorphisms with Alzheimer's disease

1 reference

12 December 2020

?1-Antichymotrypsin Binding to Alzheimer A? Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro

1 reference

12 December 2020

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

1 reference

12 December 2020

Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation

1 reference

12 December 2020

The essential role of inflammation and induced gene expression in the pathogenic pathway of Alzheimer's disease

1 reference

12 December 2020

APOE*4-associated Alzheimer's disease risk is modified by alpha 1-antichymotrypsin polymorphism.

1 reference

12 December 2020

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

12 December 2020

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

1 reference

12 December 2020

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA.

1 reference

12 December 2020

Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation

1 reference

12 December 2020

Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

1 reference

12 December 2020

Anti-inflammatory drugs and Alzheimer disease.

1 reference

12 December 2020

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

1 reference

12 December 2020

Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism.

1 reference

12 December 2020

The murine Spi-2 proteinase inhibitor locus: a multigene family with a hypervariable reactive site domain.

1 reference

12 December 2020

10.1523/JNEUROSCI.21-05-01444.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11222634%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference