(Q50092710)

24 February 2018

title

Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins (English)

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24 February 2018

9

Gregory J Gores

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24 February 2018

author name string

Edwina S Baskin-Bey

1

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24 February 2018

Wendong Huang

2

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24 February 2018

Norihisa Ishimura

3

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24 February 2018

Hajime Isomoto

4

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24 February 2018

Steven F Bronk

5

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24 February 2018

Karen Braley

6

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24 February 2018

Ruth W Craig

7

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24 February 2018

David D Moore

8

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24 February 2018

language of work or name

English

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publication date

1 July 2006

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24 February 2018

published in

Hepatology

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24 February 2018

volume

44

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24 February 2018

issue

1

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24 February 2018

page(s)

252-262

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24 February 2018

Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications

cites work

1 reference

Inhibition of Fas/FasL mRNA expression and TNF-alpha release in concanavalin A-induced liver injury in mice by bicyclol

21 January 2018

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Apoptosis and liver disease

21 January 2018

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7 January 2021

Cell death: critical control points

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7 January 2021

Lethal effect of the anti-Fas antibody in mice

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7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

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7 January 2021

Apoptosis mediated by the Fas system in the fulminant hepatitis by hepatitis B virus.

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7 January 2021

Apoptotic pathways in primary biliary cirrhosis and autoimmune hepatitis

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7 January 2021

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

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7 January 2021

Apoptosis and the expression of Fas and Fas ligand (FasL) antigen in rejection and reinfection in liver allograft specimens

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7 January 2021

Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice

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7 January 2021

The TNF and TNF receptor superfamilies: integrating mammalian biology

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7 January 2021

Acetaminophen-induced inhibition of Fas receptor-mediated liver cell apoptosis: mitochondrial dysfunction versus glutathione depletion

1 reference

7 January 2021

The Bcl-2 family: roles in cell survival and oncogenesis.

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7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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7 January 2021

Death by association: BH3 domain-only proteins and liver injury

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7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

7 January 2021

Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity

1 reference

7 January 2021

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

1 reference

7 January 2021

A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR.

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7 January 2021

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

1 reference

7 January 2021

CAR, the continuously advancing receptor, in drug metabolism and disease

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7 January 2021

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

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7 January 2021

Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver

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7 January 2021

Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.

1 reference

7 January 2021

cFLIP-L inhibits p38 MAPK activation: an additional anti-apoptotic mechanism in bile acid-mediated apoptosis

1 reference

7 January 2021

Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR.

1 reference

7 January 2021

Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells

1 reference

7 January 2021

Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm reperfusion injury

1 reference

7 January 2021

Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis.

1 reference

7 January 2021

Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in mice

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7 January 2021

Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2.

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7 January 2021

Sex difference in the proliferative response of mouse hepatocytes to treatment with the CAR ligand, TCPOBOP.

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7 January 2021

Nuclear dynamics of PCNA in DNA replication and repair

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7 January 2021

Critical contribution of liver natural killer T cells to a murine model of hepatitis

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7 January 2021

Critical roles of TRAIL in hepatic cell death and hepatic inflammation.

1 reference

7 January 2021

Mechanism of hepatocytes apoptosis induced by the proapoptosis protein Bid

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7 January 2021

The role of BH3-only proteins in the immune system

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7 January 2021

Hepatocyte growth factor induces Mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt.

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7 January 2021

The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity

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7 January 2021

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

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7 January 2021

A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification

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7 January 2021

Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner

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7 January 2021

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

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7 January 2021

Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury

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7 January 2021

Identifiers

DOI

10.1002/HEP.21236

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24 February 2018

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24 February 2018