(Q50299365)

English

TRAF1 is cleaved by caspases

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5634228)

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Statements

biological process

1 reference

8 July 2022

Regulation of TNFR1 signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5634228

1 reference

8 July 2022

TNF receptor associated factor 1

1

object of statement has role

1 reference

8 July 2022

TNF receptor associated factor 1

1

object of statement has role

1 reference

8 July 2022

active caspase-8 [cytosol]

1

object of statement has role

1 reference

8 July 2022

Caspase-mediated cleavage converts the tumor necrosis factor (TNF) receptor-associated factor (TRAF)-1 from a selective modulator of TNF receptor signaling to a general inhibitor of NF-kappaB activation

1 reference

8 July 2022

TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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