(Q50789819)

19 March 2018

title

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. (English)

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19 March 2018

author name string

Galzi JL

1

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19 March 2018

Devillers-Thiéry A

2

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19 March 2018

Hussy N

3

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19 March 2018

Bertrand S

4

1 reference

19 March 2018

Changeux JP

5

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19 March 2018

Bertrand D

6

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19 March 2018

language of work or name

English

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publication date

1 October 1992

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19 March 2018

published in

Nature

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19 March 2018

volume

359

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19 March 2018

page(s)

500-505

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19 March 2018

issue

6395

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19 March 2018

https://scigraph.springernature.com/pub.10.1038/359500a0

exact match

0 references

cites work

Ligand-gated ion channels in the brain: the amino acid receptor superfamily

1 reference

7 January 2021

Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain

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7 January 2021

The GABAA receptor family: molecular and functional diversity

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Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

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7 January 2021

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: serine-262 of the delta subunit is labeled by [3H]chlorpromazine

1 reference

7 January 2021

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

1 reference

7 January 2021

The noncompetitive blocker [3H]chlorpromazine labels three amino acids of the acetylcholine receptor gamma subunit: implications for the alpha-helical organization of regions MII and for the structure of the ion channel

1 reference

7 January 2021

Location of a delta-subunit region determining ion transport through the acetylcholine receptor channel

1 reference

7 January 2021

Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance

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7 January 2021

Fast Kinetic Studies on the Allosteric Interactions between Acetylcholine Receptor and Local Anesthetic Binding Sites

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7 January 2021

Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization

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7 January 2021

A study of the desensitization produced by acetylcholine at the motor end-plate

1 reference

7 January 2021

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1 reference

7 January 2021

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1 reference

7 January 2021

Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

1 reference

7 January 2021

Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor

1 reference

7 January 2021

Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain

1 reference

7 January 2021

Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones

1 reference

7 January 2021

An open-channel blocker interacts with adjacent turns of α-helices in the nicotinic acetylcholine receptor

1 reference

7 January 2021

A ring of uncharged polar amino acids as a component of channel constriction in the nicotinic acetylcholine receptor

1 reference

7 January 2021

Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor

1 reference

7 January 2021

Structure of the high-affinity binding site for noncompetitive blockers of the acetylcholine receptor: [3H]chlorpromazine labels homologous residues in the beta and delta chains

1 reference

7 January 2021

Ion channel formation by synthetic transmembrane segments of the inhibitory glycine receptor — a model study

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7 January 2021

The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors

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7 January 2021

Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition

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7 January 2021

Structural determinants of ion flow through recombinant glutamate receptor channels

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7 January 2021

In the GluR1 glutamate receptor subunit a glutamine to histidine point mutation suppresses inward rectification but not calcium permeability

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7 January 2021

Calcium influx through nicotinic receptor in rat central neurons: its relevance to cellular regulation

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7 January 2021

Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors

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7 January 2021

Chloride current induced by injection of calcium into Xenopus oocytes

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7 January 2021

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

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7 January 2021

The structure of ion channels in membranes of excitable cells

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7 January 2021

Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel

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7 January 2021

Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family.

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7 January 2021

A cholinergic mechanism of inhibitory synaptic transmission in a molluscan nervous system

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7 January 2021

Ionic mechanisms of a two-component cholinergic inhibition in Aplysia neurones.

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7 January 2021

Chloride channels of biological membranes

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7 January 2021

Role of a key cysteine residue in the gating of the acetylcholine receptor.

1 reference

7 January 2021

Arrangement of the acetylcholine receptor subunits in the resting and desensitized states, determined by cryoelectron microscopy of crystallized Torpedo postsynaptic membranes

1 reference

7 January 2021

Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand

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7 January 2021

Single channels activated by high concentrations of GABA in superior cervical ganglion neurones of the rat.

1 reference

7 January 2021

Cloning and expression of the 58 kd beta subunit of the inhibitory glycine receptor

1 reference

7 January 2021

The ionic basis of electrical activity in nerve and muscle

1 reference

7 January 2021

Identifiers

DOI

10.1038/359500A0

1 reference

19 March 2018

Dimensions Publication ID

1011103465

0 references

Fatcat ID

release_rl424nk455cb5gdhsimte5euoy

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rl424nk455cb5gdhsimte5euoy

24 November 2022

mapped directly with Wikidata item

PubMed ID

1383829

1 reference

19 March 2018