(Q51094782)

29 March 2018

title

Requirement for the thymus in alphabeta T lymphocyte lineage commitment. (English)

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29 March 2018

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Carlyle JR

1

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29 March 2018

Zúñiga-Pflücker JC

series ordinal

2

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29 March 2018

language of work or name

English

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publication date

1 August 1998

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29 March 2018

published in

Immunity

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29 March 2018

volume

9

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29 March 2018

page(s)

187-197

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29 March 2018

issue

2

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29 March 2018

Limited development capacity of the earliest embryonic murine thymus

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Intra- and extra-thymic expression of the pre-T cell receptor alpha gene

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Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes

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The Ikaros gene is required for the development of all lymphoid lineages

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Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells

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Involvement of transcription factors TCF-1 and GATA-3 in the initiation of the earliest step of T cell development in the thymus

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Pro-T cells in fetal thymus express c-kit and RAG-2 but do not rearrange the gene encoding the T cell receptor beta chain

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Transcription and demethylation of TCR beta gene initiate prior to the gene rearrangement in c-kit+ thymocytes with CD3 expression: evidence of T cell commitment in the thymus.

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Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop

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Induction of TCR gene rearrangements in uncommitted stem cells by a subset of IL-7 producing, MHC class-II-expressing thymic stromal cells.

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7 January 2021

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7 January 2021

A population of early fetal thymocytes expressing Fc gamma RII/III contains precursors of T lymphocytes and natural killer cells

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7 January 2021

Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.

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7 January 2021

Generation of intestinal T cells from progenitors residing in gut cryptopatches

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7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

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7 January 2021

Early T lymphocyte progenitors

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7 January 2021

Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor beta chain

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7 January 2021

Development and characterization of v-myc/v-raf-transformed murine fetal thymocyte cell lines

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7 January 2021

T cell receptor (TCR)-beta gene recombination: dissociation from cell cycle regulation and developmental progression during T cell ontogeny

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7 January 2021

Biology of natural killer cells

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7 January 2021

Thymus-neuroendocrine interactions in extrathymic T cell development

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7 January 2021

Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny

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7 January 2021

Generation of lytic natural killer 1.1+, Ly-49- cells from multipotential murine bone marrow progenitors in a stroma-free culture: definition of cytokine requirements and developmental intermediates

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7 January 2021

Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation.

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7 January 2021

Regulation of thymocyte development from immature progenitors.

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7 January 2021

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Identifiers

DOI

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29 March 2018

PubMed ID

9729039

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29 March 2018