(Q51372283)

4 April 2018

title

Methodologies to study the induction of rat hepatic and intestinal cytochrome P450 3A at the mRNA, protein, and catalytic activity level. (English)

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4 April 2018

4

Greenblatt DJ

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4 April 2018

Lisa L. von Moltke

series ordinal

2

object named as

von Moltke LL

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4 April 2018

author name string

Cotreau MM

series ordinal

1

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4 April 2018

Beinfeld MC

series ordinal

3

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4 April 2018

publication date

1 January 2000

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4 April 2018

Journal of Pharmacological and Toxicological Methods

published in

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4 April 2018

volume

43

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4 April 2018

issue

1

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4 April 2018

page(s)

41-54

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4 April 2018

Cytochrome P450 of small intestinal epithelial cells. Immunochemical characterization of the increase in cytochrome P450 caused by phenobarbital

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Influence of polyethylene glycol and acetone on the in vitro biotransformation of tamoxifen and alprazolam by human liver microsomes

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Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

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Inhibition of human cytochrome P450-3A isoforms by fluoxetine and norfluoxetine: in vitro and in vivo studies

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7 January 2021

Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences

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A novel cytochrome P450 3A isoenzyme in rat intestinal microsomes

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7 January 2021

Dose-dependent intestinal and hepatic first-pass metabolism of midazolam, a cytochrome P450 3A substrate with differently modulated enzyme activity in rats.

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7 January 2021

Dexamethasone responsiveness of a major glucocorticoid-inducible CYP3A gene is mediated by elements unrelated to a glucocorticoid receptor binding motif

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Small Intestinal Cytochromes P450

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cDNA cloning and characterization of a novel member of steroid-induced cytochrome P450 3A in rats

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First-pass metabolism of cyclosporin by the gut

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A major glucocorticoid-inducible P450 in rat liver is not P450 3A1.

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers

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7 January 2021

Differences between small and large intestine and liver in the inducibility of microsomal enzymes in response to stimulation by phenobarbitone and betanaphthoflavone in the diet

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7 January 2021

Isolation and characterization of a new rat P450 (CYP3A18) cDNA encoding P450(6)beta-2 catalyzing testosterone 6 beta- and 16 alpha-hydroxylations

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7 January 2021

Structure and expression of the rat CYP3A1 gene: isolation of the gene (P450/6betaB) and characterization of the recombinant protein

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First-pass metabolism of midazolam by the human intestine.

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Unchanged cytochrome P450 3A (CYP3A) expression and metabolism of midazolam, triazolam, and dexamethasone in mdr(-/-) mouse liver microsomes.

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Cytochromes P-450 in the intestinal mucosa of man

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7 January 2021

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7 January 2021

Effects of ketoconazole on digoxin absorption and disposition in rat.

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7 January 2021

Preparation of microsomes with calcium

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7 January 2021

Human cytochrome P450s: selectivity and measurement in vivo

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7 January 2021

Molecular genetics of the human cytochrome P450 monooxygenase superfamily

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7 January 2021

A novel CYP3 gene from female rats

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7 January 2021

In vitro and in vivo drug interactions involving human CYP3A.

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7 January 2021

Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: effect of ketoconazole.

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7 January 2021

Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

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7 January 2021

Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants

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7 January 2021

Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

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7 January 2021

Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.

1 reference

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7 January 2021

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

1 reference

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7 January 2021

Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-8719%2800%2900086-1

7 January 2021

10.1016/S1056-8719(00)00086-1

Identifiers

DOI

1 reference

4 April 2018

1 reference

4 April 2018