(Q51408849)

2 July 2019

title

Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1. (English)

1 reference

2 July 2019

1 reference

2

Alexander Wlodawer

1 reference

2 July 2019

author name string

Di Zhang

series ordinal

1

1 reference

2 July 2019

Jacek Lubkowski

series ordinal

3

1 reference

2 July 2019

language of work or name

English

0 references

publication date

7 October 2016

1 reference

2 July 2019

Journal of Molecular Biology

published in

1 reference

2 July 2019

volume

428

1 reference

2 July 2019

issue

23

1 reference

2 July 2019

page(s)

4651-4668

1 reference

2 July 2019

Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase

cites work

1 reference

12 December 2020

The Structural Basis for Class II Cytokine Receptor Recognition by JAK1

1 reference

12 December 2020

Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1.

1 reference

12 December 2020

Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases

1 reference

12 December 2020

Structural analysis of cytokines comprising the IL-10 family

1 reference

12 December 2020

Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases

1 reference

12 December 2020

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2

1 reference

12 December 2020

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

1 reference

12 December 2020

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

12 December 2020

Cytokine receptor signaling through the Jak-Stat-Socs pathway in disease.

1 reference

12 December 2020

Mechanism of activation of protein kinase JAK2 by the growth hormone receptor

1 reference

12 December 2020

Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

1 reference

12 December 2020

Insights into cytokine-receptor interactions from cytokine engineering

1 reference

12 December 2020

IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression

1 reference

12 December 2020

Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases

1 reference

12 December 2020

Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

1 reference

12 December 2020

Structure of an extracellular gp130 cytokine receptor signaling complex

1 reference

12 December 2020

The Jak1 SH2 domain does not fulfill a classical SH2 function in Jak/STAT signaling but plays a structural role for receptor interaction and up-regulation of receptor surface expression

1 reference

12 December 2020

The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling

1 reference

12 December 2020

Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family

1 reference

12 December 2020

Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog

1 reference

12 December 2020

Automated protein model building combined with iterative structure refinement

1 reference

12 December 2020

Biological activity of interleukins-28 and -29: comparison with type I interferons

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Structural biology of shared cytokine receptors

1 reference

12 December 2020

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling

1 reference

12 December 2020

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

12 December 2020

Solving structures of protein complexes by molecular replacement with Phaser

1 reference

12 December 2020

The molecular regulation of Janus kinase (JAK) activation

1 reference

12 December 2020

Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling

1 reference

12 December 2020

HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes

1 reference

12 December 2020

Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation

1 reference

12 December 2020

REFMAC5 for the refinement of macromolecular crystal structures

1 reference

12 December 2020

Improved molecular replacement by density- and energy-guided protein structure optimization

1 reference

12 December 2020

Structural requirements of the interleukin-6 signal transducer gp130 for its interaction with Janus kinase 1: the receptor is crucial for kinase activation

1 reference

12 December 2020

Coot: model-building tools for molecular graphics

1 reference

12 December 2020

Crystal Structure of the FERM-SH2 Module of Human Jak2.

1 reference

12 December 2020

Structural insights into the common γ-chain family of cytokines and receptors from the interleukin-7 pathway

1 reference

12 December 2020

Computational and functional analysis of the putative SH2 domain in Janus Kinases

1 reference

12 December 2020

Novel interferon-lambdas induce antiproliferative effects in neuroendocrine tumor cells

1 reference

12 December 2020

JAK and STAT signaling molecules in immunoregulation and immune-mediated disease

1 reference

12 December 2020

Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

1 reference

12 December 2020

10.1016/J.JMB.2016.10.005

Identifiers

DOI

1 reference

2 July 2019

PMC publication ID

6288811

1 reference

2 July 2019

PubMed publication ID

27725180

1 reference

2 July 2019