(Q51423763)

English

Anxiolytic effects of the neuroactive steroid pregnanolone (3 alpha-OH-5 beta-pregnan-20-one) after microinjection in the dorsal hippocampus and lateral septum.

scientific article published in December 1999

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scholarly article

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

Anxiolytic effects of the neuroactive steroid pregnanolone (3 alpha-OH-5 beta-pregnan-20-one) after microinjection in the dorsal hippocampus and lateral septum. (English)

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

author name string

D Bitran

1

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

M Dugan

2

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

P Renda

3

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

R Ellis

4

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

M Foley

5

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

language of work or name

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publication date

1 December 1999

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

850

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

217-224

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Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

1-2

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Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively.

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Stress-induced increase in brain neuroactive steroids: antagonism by abecarnil

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The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations

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Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

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Hippocampal mossy fibres: implication in novelty reactions or in anxiety behaviours?

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Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

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Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function.

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Corticosterone is permissive to the anxiolytic effect that results from the blockade of hippocampal mineralocorticoid receptors.

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Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors.

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Subcortical mechanisms in emotional behavior: the duration of affective changes following septal and habenular lesions in the albino rat.

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The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors.

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Anxiolytic properties of endogenously occurring pregnanediols in two rodent models of anxiety.

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Withdrawal from the endogenous steroid progesterone results in GABAA currents insensitive to benzodiazepine modulation in rat CA1 hippocampus

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The neurosteroid, 3 alpha-hydroxy-5 alpha-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats.

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Low doses of muscimol produce anticonflict actions in the lateral septum of the rat.

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Flumazenil blocks the anxiolytic action of allopregnanolone.

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Regulation of the prefrontal cortical dopamine system by the neuroactive steroid 3a,21-dihydroxy-5a-pregnane-20-one

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The influence of the gamma 2L subunit on the modulation of responses to GABAA receptor activation

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Tetrahydro-beta-carboline micro-injected into the hippocampus induces an anxiety-like state in the rat.

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Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic

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Importance of hypothalamic function to stressor-induced responsiveness of the GABAA receptor in the cerebral cortex: a non-corticosterone influence.

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Intra-hippocampal buspirone in animal models of anxiety.

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Interaction between 17 beta-oestradiol and 3 alpha-hydroxy-5 alpha-pregnane-20-one in the control of neuronal excitability in slices from the CA1 hippocampus in vitro of guinea-pigs and rats.

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Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

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The anaesthetic potency of 3 alpha-hydroxy-5 alpha-pregnan-20-one and 3 alpha-hydroxy-5 beta-pregnan-20-one determined with an intravenous EEG-threshold method in male rats.

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7 January 2021

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

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Excitotoxic lesions of the septum produce anxiolytic effects in the elevated plus-maze and the shock-probe burying tests

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The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines.

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The neuroanatomical specificity of the anxiolytic effects of intra-septal infusions of midazolam.

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Anti-anxiety effects of progesterone and some of its reduced metabolites: an evaluation using the burying behavior test

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Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

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Progesterone enhances inhibitory responses of cerebellar Purkinje cells mediated by the GABAA receptor subtype

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Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.

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Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum.

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Hippocampal mineralocorticoid, but not glucocorticoid, receptors modulate anxiety-like behavior in rats.

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Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of the 5-HT3 receptor antagonists.

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Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-HT1A receptor agonists.

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Potency of lipid and protein formulation of 5 alpha-pregnanolone at induction of anaesthesia and the corresponding regional brain distribution.

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Comparative behavioral characterization of the neuroactive steroids 3 alpha-OH,5 alpha-pregnan-20-one and 3 alpha-OH,5 beta-pregnan-20-one in rodents.

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Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

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The role of the lateral septum in anxiolysis.

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Delta subunit inhibits neurosteroid modulation of GABAA receptors.

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Dissociations among the anxiolytic effects of septal, hippocampal, and amygdaloid lesions.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Dissociating the anti-fear effects of septal and amygdaloid lesions using two pharmacologically validated models of rat anxiety.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0006-8993(99)02150-2

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

1 reference

Europe PubMed Central

5 April 2018

http://europepmc.org/abstract/MED/10629767

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