(Q51604644)

English

Neurochemical and behavioural investigations of the NMDA receptor-associated glycine site in the rat striatum: functional implications for treatment of parkinsonian symptoms.

scientific article published in May 1995

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7675950%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

Neurochemical and behavioural investigations of the NMDA receptor-associated glycine site in the rat striatum: functional implications for treatment of parkinsonian symptoms (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7675950%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

Parkinson's disease

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Jonathan M. Brotchie

3

1 reference

Europe PubMed Central

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23 October 2019

author name string

C B Carroll

1

1 reference

Europe PubMed Central

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23 October 2019

V Holloway

2

1 reference

Europe PubMed Central

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23 October 2019

I J Mitchell

4

1 reference

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23 October 2019

publication date

1 May 1995

1 reference

Europe PubMed Central

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23 October 2019

Psychopharmacology

1 reference

Europe PubMed Central

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23 October 2019

119

1 reference

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23 October 2019

55-65

1 reference

Europe PubMed Central

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23 October 2019

1

1 reference

Europe PubMed Central

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23 October 2019

https://scigraph.springernature.com/pub.10.1007/bf02246054

0 references

Different modes of action of 3-amino-1-hydroxy-2-pyrrolidone (HA-966) and 7-chlorokynurenic acid in the modulation of N-methyl-D-aspartate-sensitive glutamate receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural mechanisms in disorders of movement.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic mechanisms of glycine requirement for N-methyl-d-aspartate channel activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA antagonists potentiate antiparkinsonian actions of L-dopa in monoamine-depleted rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective R-(+) enantiomer of HA-966 displays anxiolytic effects in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HA-966 antagonizes N-methyl-D-aspartate receptors through a selective interaction with the glycine modulatory site

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and regional distribution of strychnine-insensitive [3H]glycine binding sites in rat brain by quantitative receptor autoradiography

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-dopamine interactions in the basal ganglia: relationship to Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenic acid and AP5 distinguish between NMDA receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine modulation of NMDA-evoked release of [3H]acetylcholine and [3H]dopamine from rat striatal slices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A glycine site associated with N-methyl-D-aspartic acid receptors: characterization and identification of a new class of antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The AMPA receptor antagonist NBQX has antiparkinsonian effects in monoamine-depleted rats and MPTP-treated monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-like character of the (R)-enantiomer of 1-hydroxy-3-amino-pyrrolid-2-one (HA-966)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinate differentiates between forebrain and cerebellar NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HA-966 (1-hydroxy-3-aminopyrrolidone-2) selectively reduces N-methyl-D-aspartate (NMDA)-mediated brain damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a [3H]glycine recognition site as a modulatory site of the N-methyl-D-aspartate receptor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different stereoselectivity of the enantiomers of HA-966 (3-amino-1-hydroxy-2-pyrrolidinone) for neuroprotective and anticonvulsant actions in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine is a coagonist at the NMDA receptor/channel complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modulation of the associated glycine recognition site by competitive N-methyl-D-aspartate receptor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between the glutamate and glycine recognition sites of the N-methyl-D-aspartate receptor from rat brain, as revealed from radioligand binding studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injection of the competitive NMDA receptor antagonist AP-5 into the nucleus accumbens of monoamine-depleted mice induces pronounced locomotor stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and characterization of the rat NMDA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate recognition site ligands modulate activity at the coupled glycine recognition site

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity of N-Methyl-D-Aspartate Receptors Regulating the Release of Dopamine and Acetylcholine from Striatal Slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic acid: regional variations in neuronal sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On central muscle relaxants, strychnine-insensitive glycine receptors and two old drugs: zoxazolamine and HA-966

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortically evoked excitatory synaptic transmission in the cat red nucleus is antagonised by D-AP5 but not by D-AP7

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural mechanisms underlying parkinsonian symptoms based upon regional uptake of 2-deoxyglucose in monkeys exposed to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for direct interactions between the NMDA and glycine recognition sites in brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular diversity of the NMDA receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine potentiates the NMDA response in cultured mouse brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel N-methyl-D-aspartate receptor population in the rat medial thalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselectivity for the (R)-enantiomer of HA-966 (1-hydroxy-3-aminopyrrolidone-2) at the glycine site of the N-methyl-D-aspartate receptor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/7675950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF02246054

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7675950%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7675950%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

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