(Q51752072)

11 April 2018

title

Progress and prospects for targeting Hsp90 to treat fungal infections. (English)

1 reference

11 April 2018

author

Amanda O Veri

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Leah E Cowen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

author name string

Amanda Veri

1

1 reference

11 April 2018

Leah E Cowen

2

1 reference

11 April 2018

publication date

20 February 2014

1 reference

11 April 2018

published in

Parasitology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

volume

141

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

1127-1137

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity

7 June 2020

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Regulatory circuitry governing fungal development, drug resistance, and disease.

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Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence

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7 January 2021

Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution.

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7 January 2021

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence

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7 January 2021

Role of HSP90 in salt stress tolerance via stabilization and regulation of calcineurin

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7 January 2021

Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function

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7 January 2021

Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi and evaluation of its inhibitor as a candidate drug

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7 January 2021

S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities

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7 January 2021

Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs

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7 January 2021

Calcineurin is essential for survival during membrane stress in Candida albicans

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7 January 2021

Calcineurin governs thermotolerance and virulence of Cryptococcus gattii

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7 January 2021

The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype.

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7 January 2021

Targeting the dynamic HSP90 complex in cancer

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7 January 2021

Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus

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7 January 2021

Mapping the Hsp90 genetic interaction network in Candida albicans reveals environmental contingency and rewired circuitry

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7 January 2021

Hidden killers: human fungal infections

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7 January 2021

Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus

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7 January 2021

Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.

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7 January 2021

Hsp90 and environmental stress transform the adaptive value of natural genetic variation

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7 January 2021

Hsp90 molecular chaperone inhibitors: are we there yet?

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7 January 2021

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

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7 January 2021

A repurposing strategy identifies novel synergistic inhibitors of Plasmodium falciparum heat shock protein 90.

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7 January 2021

Heat-shock protein hsp90 governs the activity of pp60v-src kinase

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7 January 2021

PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Trithorax requires Hsp90 for maintenance of active chromatin at sites of gene expression

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Oncogenic mutations reduce the stability of SRC kinase.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Genetic architecture of Hsp90-dependent drug resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

How to build a biofilm: a fungal perspective

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Plasticity of the Hsp90 chaperone machine in divergent eukaryotic organisms

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Calcineurin is essential for virulence in Candida albicans

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

The fungal Achilles' heel: targeting Hsp90 to cripple fungal pathogens.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Pho85, Pcl1, and Hms1 signaling governs Candida albicans morphogenesis induced by high temperature or Hsp90 compromise.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Candida albicans morphogenesis and host defence: discriminating invasion from colonization.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Genetic control of Candida albicans biofilm development

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Role of the Slt2 mitogen-activated protein kinase pathway in cell wall integrity and virulence in Candida glabrata

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 orchestrates stress response signaling governing fungal drug resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Estimating the cost of nosocomial candidemia in the united states

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance.

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

The Hsp90 co-chaperone Sgt1 governs Candida albicans morphogenesis and drug resistance

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Candida albicans biofilm development, modeling a host-pathogen interaction.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

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https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p).

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Epidemiology of invasive mycoses in North America

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Aspergillosis case-fatality rate: systematic review of the literature

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Managing drug resistance in cancer: lessons from HIV therapy

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Tackling Human Fungal Infections

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Our current understanding of fungal biofilms

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Between genotype and phenotype: protein chaperones and evolvability

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

HSP90-buffered genetic variation is common in Arabidopsis thaliana

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

A purine analog synergizes with chloroquine (CQ) by targeting Plasmodium falciparum Hsp90 (PfHsp90)

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 as a capacitor for morphological evolution

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Biofilms and their role in the resistance of pathogenic Candida to antifungal agents

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 governs dispersion and drug resistance of fungal biofilms

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Epidemiology of invasive candidiasis: a persistent public health problem

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 as a capacitor of phenotypic variation

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Emerging fungal threats to animal, plant and ecosystem health

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Advancing the development of tuberculosis therapy

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

An acetylation site in the middle domain of Hsp90 regulates chaperone function

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Stress, drugs, and evolution: the role of cellular signaling in fungal drug resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Harmine is a potent antimalarial targeting Hsp90 and synergizes with chloroquine and artemisinin

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

HSP90 affects the expression of genetic variation and developmental stability in quantitative traits

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013002072

7 January 2021

10.1017/S0031182013002072

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24560124%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference