(Q51767884)

English

Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound.

scientific article published on 14 March 2009

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scholarly article

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound. (English)

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

Chiara Gabbiani

2

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

Giuseppe Pieraccini

4

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

object named as

Luigi Messori

7

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object named as

Paul J Dyson

6

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author name string

Elena Michelucci

3

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

Gloriano Moneti

5

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

publication date

14 March 2009

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

Journal of Biological Inorganic Chemistry

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

14

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

761-770

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

5

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

describes a project that uses

mass spectrometry

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inferred from title

https://scigraph.springernature.com/pub.10.1007/s00775-009-0489-5

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From bench to bedside--preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A).

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https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ruthenium (II)-derived organometallic compounds induce cytostatic and cytotoxic effects on mammalian cancer cell lines through p53-dependent and p53-independent mechanisms.

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https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of cisplatin and transplatin with proteins. Comparison of binding kinetics, binding sites and reactivity of the Pt-protein adducts of cisplatin and transplatin towards biological nucleophiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of cisplatin coordination sites in cellular Escherichia coli DNA-binding proteins by combined biphasic liquid chromatography and ESI tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metal-based antitumour drugs in the post genomic era.

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https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

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The Orbitrap: a new mass spectrometer

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https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor active trans-platinum compounds

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https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA modifications by antitumor platinum and ruthenium compounds: their recognition and repair.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the metastatic progression of breast cancer with an organometallic ruthenium compound.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin: structures, functions, mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability of an organometallic ruthenium-ubiquitin adduct in the presence of glutathione: relevance to antitumour activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome C-mediated apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide dismutase--applications and relevance to human diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platinum(IV) anticancer complexes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of platinum anticancer drug protein-binding sites using a top-down mass spectrometric approach

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ruthenium anticancer drugs and proteins: a study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of new methodologies for the mass spectrometry study of bioorganic macromolecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrospray mass spectrometry (ESI-MS) in the study of metal-ligand solution equilibria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of metallothionein-2 with platinum-modified 5'-guanosine monophosphate and DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid metabolite identification with sub parts-per-million mass accuracy from biological matrices by direct infusion nanoelectrospray ionization after clean-up on a ZipTip and LTQ/Orbitrap mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mass spectrometric and molecular modelling study of cisplatin binding to transferrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct introduction of biological samples into a LTQ-Orbitrap hybrid mass spectrometer as a tool for fast metabolome analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of (eta6-arene)ruthenium(II) protein binding sites in E. coli cells by combined multidimensional liquid chromatography and ESI tandem mass spectrometry: specific binding of [(eta6-p-cymene)RuCl2 (DMSO)] to stress-regulated proteins an

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exploring Metallodrug–Protein Interactions by ESI Mass Spectrometry: The Reaction of Anticancer Platinum Drugs with Horse Heart Cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Applications of ESI-MS in drug discovery: interrogation of noncovalent complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ruthenium antimetastatic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precision mapping of the metabolome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reaction of Zn7Metallothionein withcis- andtrans-[Pt(N-donor)2Cl2] Anticancer Complexes: trans-PtIIComplexes Retain Their N-Donor Ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ruthenium(II)-arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53-JNK pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ESI–MS Characterisation of Protein Adducts of Anticancer Ruthenium(II)-Arene PTA (RAPTA) Complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/19288144

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00775-009-0489-5

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/19288144

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