(Q51770836)

English

Human prostaglandin H synthase (hPHS)-1- and hPHS-2-dependent bioactivation, oxidative macromolecular damage, and cytotoxicity of dopamine, its precursor, and its metabolites

scientific article published on November 13, 2010

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

Human prostaglandin H synthase (hPHS)-1- and hPHS-2-dependent bioactivation, oxidative macromolecular damage, and cytotoxicity of dopamine, its precursor, and its metabolites (English)

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

0 references

1 reference

based on heuristic

inferred from title

author name string

Annmarie Ramkissoon

1

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

Peter G. Wells

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078384

27 August 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21078384

27 August 2024

publication date

13 November 2010

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

full work available at URL

https://api.elsevier.com/content/article/PII:S089158491001364X?httpAccept=text/xml

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

https://api.elsevier.com/content/article/PII:S089158491001364X?httpAccept=text/plain

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Free Radical Biology and Medicine

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

50

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

2

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

295-304

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer

2

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs

4

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cyclooxygenases and the central nervous system

5

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

6

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Prostaglandin synthase-mediated metabolism of carcinogens and a potential role for peroxyl radicals as reactive intermediates

7

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Prostaglandin hydroperoxidase-dependent oxidation of phenylbutazone: relationship to inhibition of prostaglandin cyclooxygenase

10

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Free radical intermediates of phenytoin and related teratogens. Prostaglandin H synthase-catalyzed bioactivation, electron paramagnetic resonance spectrometry, and photochemical product analysis.

11

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice.

12

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cyclooxygenase-2 is involved in oxidative damage and alpha-synuclein accumulation in dopaminergic cells

14

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Oxidation and cytotoxicity of 6-OHDA are mediated by reactive intermediates of COX-2 overexpressed in PC12 cells.

15

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Dopaminergic neurotoxicity by 6-OHDA and MPP+: differential requirement for neuronal cyclooxygenase activity

16

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Comparison of structural stabilities of prostaglandin H synthase-1 and -2.

17

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

18

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells

20

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy

21

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up.

22

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells

25

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro

26

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

27

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells

28

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects

30

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Dopamine- and L-beta-3,4-dihydroxyphenylalanine hydrochloride (L-Dopa)-induced cytotoxicity towards catecholaminergic neuroblastoma SH-SY5Y cells. Effects of oxidative stress and antioxidative factors

31

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Prostaglandin H synthase-1-catalyzed bioactivation of neurotransmitters, their precursors, and metabolites: oxidative DNA damage and electron spin resonance spectroscopy studies

32

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Prostaglandin H synthase-catalyzed bioactivation of amphetamines to free radical intermediates that cause CNS regional DNA oxidation and nerve terminal degeneration

33

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Reduced 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy)-initiated oxidative DNA damage and neurodegeneration in prostaglandin H synthase-1 knockout mice

34

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Embryonic prostaglandin H synthase-2 (PHS-2) expression and benzo[a]pyrene teratogenicity in PHS-2 knockout mice

35

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity

36

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Comparison of the properties of prostaglandin H synthase-1 and -2.

37

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic

38

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cellular regulation of prostaglandin H synthase catalysis

39

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Activation of heterocyclic amines by combinations of prostaglandin H synthase-1 and -2 with N-acetyltransferase 1 and 2

40

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Activation of 2-aminofluorene by prostaglandin endoperoxide H synthase-2

41

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Carcinogen substrate specificity of human COX-1 and COX-2.

42

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

43

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

A quantitative study on the nigro-neostriatal dopamine neuron system in the rat.

44

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain

45

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells.

46

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation

47

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Oxidative stress and gene regulation

50

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kappaB promoter element.

51

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

8-hydroxydeoxyguanosine causes death of human leukemia cells deficient in 8-oxoguanine glycosylase 1 activity by inducing apoptosis

52

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits

53

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Formation of DNA adducts and oxidative base damage by copper mediated oxidation of dopamine and 6-hydroxydopamine

54

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2.

55

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

On the neurotoxicity mechanism of leukoaminochrome o-semiquinone radical derived from dopamine oxidation: mitochondria damage, necrosis, and hydroxyl radical formation

57

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Inhibition of brain mitochondrial respiration by dopamine and its metabolites: implications for Parkinson's disease and catecholamine-associated diseases

58

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

One-electron oxidation of catecholamines generates free radicals with an in vitro toxicity correlating with their lifetime

59

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons

60

1 reference

10.1016/J.FREERADBIOMED.2010.11.010

https://api.crossref.org/works/10.1016/J.FREERADBIOMED.2010.11.010

27 August 2024

Identifiers

10.1016/J.FREERADBIOMED.2010.11.010

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 April 2018

http://europepmc.org/abstract/MED/21078384

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q51770836&oldid=2237264224"