(Q51966311)

19 April 2018

title

Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration. (English)

1 reference

19 April 2018

author name string

J Ramesh Babu

1

1 reference

19 April 2018

M Lamar Seibenhener

2

1 reference

19 April 2018

Junmin Peng

3

1 reference

19 April 2018

Anna-Lena Strom

4

1 reference

19 April 2018

Robert Kemppainen

5

1 reference

19 April 2018

Nancy Cox

6

1 reference

19 April 2018

Haining Zhu

7

1 reference

19 April 2018

Michael C Wooten

8

1 reference

19 April 2018

María T Diaz-Meco

9

1 reference

19 April 2018

Jorge Moscat

10

1 reference

19 April 2018

Marie W Wooten

11

1 reference

19 April 2018

language of work or name

English

0 references

publication date

1 July 2008

1 reference

19 April 2018

Journal of Neurochemistry

published in

1 reference

19 April 2018

volume

106

1 reference

19 April 2018

page(s)

107-120

1 reference

19 April 2018

issue

1

1 reference

19 April 2018

Ubiquitin-mediated activation of TAK1 and IKK.

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Beta 1-integrins are required for hippocampal AMPA receptor-dependent synaptic transmission, synaptic plasticity, and working memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Insulin resistance syndrome and Alzheimer's disease: age- and obesity-related effects on memory, amyloid, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Neurotrophins and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Ubiquitin-mediated sequestration of normal cellular proteins into polyglutamine aggregates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Chaperones increase association of tau protein with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Mice with the deleted neurofilament of low molecular weight (Nefl) gene: 2. Effects on motor functions and spatial orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Peripheral hyperinsulinemia promotes tau phosphorylation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Brain-derived neurotrophic factor and the metabolic syndrome: more than just a hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Tau filament formation in transgenic mice expressing P301L tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

p62 modulates Akt activity via association with PKCzeta in neuronal survival and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Autosomal dominant inclusion body myopathy, Paget disease of bone, and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Association of a functional BDNF polymorphism and anxiety-related personality traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Granular tau oligomers as intermediates of tau filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Regulation of interleukin receptor-associated kinase (IRAK) phosphorylation and signaling by iota protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Signal integration and diversification through the p62 scaffold protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Differential expression of atypical PKCs in the adult mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Role for neuronal insulin resistance in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Atypical protein kinase C in neurodegenerative disease II: PKCiota/lambda in tauopathies and alpha-synucleinopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Peptidase activities of the 20/26S proteasome and a novel protease in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05340.X

10.1111/J.1471-4159.2008.05340.X

21 January 2018

Identifiers

DOI

1 reference

19 April 2018

PubMed ID

18346206

1 reference

19 April 2018