(Q52005548)

19 April 2018

title

Genetic Reprogramming of Primary Human T Cells Reveals Functional Plasticity in Th Cell Differentiation (English)

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

12 March 2024

1 reference

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

12 March 2024

author name string

Donghui Ni

3

1 reference

19 April 2018

Kinya Nagata

4

1 reference

19 April 2018

Arun Subramaniam

6

1 reference

19 April 2018

Derya Unutmaz

7

1 reference

19 April 2018

Mark S. Sundrud

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500650

12 March 2024

Stacy M. Grill

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500650

12 March 2024

Sefik S. Alkan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500650

12 March 2024

language of work or name

English

0 references

publication date

1 October 2003

1 reference

19 April 2018

full work available at URL

published in

Journal of Immunology

1 reference

19 April 2018

volume

171

1 reference

19 April 2018

page(s)

3542-3549

1 reference

19 April 2018

issue

7

1 reference

19 April 2018

The expanding universe of T-cell subsets: Th1, Th2 and more.

cites work

1

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Functional diversity of helper T lymphocytes

12 March 2024

2

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Cytokines induce the development of functionally heterogeneous T helper cell subsets

12 March 2024

3

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Acquisition of lymphokine-producing phenotype by CD4+ T cells

12 March 2024

4

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

12 March 2024

5

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

A novel transcription factor, T-bet, directs Th1 lineage commitment

12 March 2024

6

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Transcription: tantalizing times for T cells

12 March 2024

7

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene

12 March 2024

8

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene

12 March 2024

9

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.

12 March 2024

11

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

12 March 2024

12

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Inhibition of Th1 Development Mediated by GATA-3 through an IL-4-Independent Mechanism

12 March 2024

13

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

12 March 2024

14

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

12 March 2024

15

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

12 March 2024

16

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

12 March 2024

17

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

12 March 2024

18

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

GATA-3 significantly downregulates IFN-gamma production from developing Th1 cells in addition to inducing IL-4 and IL-5 levels

12 March 2024

19

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Regulation of IL-4 gene expression by distal regulatory elements and GATA-3 at the chromatin level

12 March 2024

20

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4.

12 March 2024

21

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms

12 March 2024

22

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

12 March 2024

23

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3

12 March 2024

24

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

12 March 2024

26

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.

12 March 2024

27

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

12 March 2024

28

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

12 March 2024

29

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The role of chemokine receptors in primary, effector, and memory immune responses

12 March 2024

30

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

12 March 2024

32

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes

12 March 2024

33

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes

12 March 2024

34

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

12 March 2024

35

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)

12 March 2024

36

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics

12 March 2024

37

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

From TCR Engagement to T Cell Activation

12 March 2024

38

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

12 March 2024

39

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

12 March 2024

40

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Functional plasticity of an antigen-specific memory CD4 T cell population.

12 March 2024

41

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Transcriptional regulation of Th1/Th2 polarization

12 March 2024

42

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

12 March 2024

43

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Selective expression of an interleukin-12 receptor component by human T helper 1 cells

12 March 2024

44

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Cutting edge: ectopic expression of the IL-12 receptor-beta 2 in developing and committed Th2 cells does not affect the production of IL-4 or induce the production of IFN-gamma.

12 March 2024

46

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

IL-12-induced reversal of human Th2 cells is accompanied by full restoration of IL-12 responsiveness and loss of GATA-3 expression.

12 March 2024

47

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

12 March 2024

48

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

12 March 2024

49

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

The interplay between the duration of TCR and cytokine signaling determines T cell polarization

12 March 2024

51

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Helper T cell differentiation is controlled by the cell cycle

12 March 2024

52

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation

12 March 2024

53

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

12 March 2024

54

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

12 March 2024

55

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

ROG, repressor of GATA, regulates the expression of cytokine genes

12 March 2024

56

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Friend of GATA is expressed in naive Th cells and functions as a repressor of GATA-3-mediated Th2 cell development

12 March 2024

57

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells.

12 March 2024

58

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Requirement of the chemokine receptor CXCR3 for acute allograft rejection

12 March 2024

59

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice

12 March 2024

61

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Mig and IP-10: CXC chemokines that target lymphocytes

12 March 2024

62

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

Mast cells in autoimmune disease

12 March 2024

65

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3542

12 March 2024

Identifiers

1 reference

19 April 2018

1 reference

19 April 2018