(Q52018427)

19 April 2018

title

CD4(+) T cell effectors can become memory cells with high efficiency and without further division. (English)

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19 April 2018

author name string

Hu H

1

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19 April 2018

Huston G

2

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19 April 2018

Duso D

3

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19 April 2018

Lepak N

4

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19 April 2018

Roman E

5

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19 April 2018

Swain SL

6

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19 April 2018

language of work or name

English

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publication date

1 August 2001

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19 April 2018

published in

Nature Immunology

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19 April 2018

volume

2

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19 April 2018

issue

8

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19 April 2018

page(s)

705-710

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19 April 2018

Class II-independent generation of CD4 memory T cells from effectors.

cites work

1 reference

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Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma

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Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation

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Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses

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Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15.

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

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Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

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Identifiers

DOI

10.1038/90643

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19 April 2018

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19 April 2018