(Q52193951)

English

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair.

scientific article published in July 1997

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scholarly article

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair. (English)

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

1 reference

based on heuristic

inferred from title

author name string

Brugarolas J

1

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

Jacks T

2

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

language of work or name

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publication date

1 July 1997

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

Nature Medicine

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

3

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

721-722

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

7

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

https://scigraph.springernature.com/pub.10.1038/nm0797-721

0 references

Identification of the breast cancer susceptibility gene BRCA2

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Transcriptional activation functions in BRCA2

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Tumor suppressor gene mutations in mice

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

Transcriptional activation by BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

21 January 2018

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 is localized in cytoplasmic tube-like invaginations in the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

7 January 2021

based on heuristic

inferred from DOI database lookup

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

7 January 2021

based on heuristic

inferred from DOI database lookup

A human BRCA1 gene knockout

1 reference

https://api.crossref.org/works/10.1038%2FNM0797-721

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/NM0797-721

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

1 reference

Europe PubMed Central

26 April 2018

http://europepmc.org/abstract/MED/9212093

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