(Q52206874)

27 April 2018

title

Regulation of thymocyte development through CD3: functional dissociation between p56lck and CD3 sigma in early thymic selection. (English)

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27 April 2018

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5

S Tonegawa

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27 April 2018

author name string

C N Levelt

1

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27 April 2018

P Mombaerts

2

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27 April 2018

B Wang

3

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27 April 2018

H Kohler

4

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27 April 2018

K Eichmann

6

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27 April 2018

C Terhorst

7

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27 April 2018

language of work or name

English

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publication date

1 August 1995

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27 April 2018

published in

Immunity

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27 April 2018

volume

3

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27 April 2018

page(s)

215-222

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27 April 2018

issue

2

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27 April 2018

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

A role for a pre-T-cell receptor in T-cell development

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Analysis and expression of a cloned pre-T cell receptor gene

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Activation events during thymic selection

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

p56lck interacts via its src homology 2 domain with the ZAP-70 kinase

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Regulation of T cell receptor (TCR)-beta locus allelic exclusion and initiation of TCR-alpha locus rearrangement in immature thymocytes by signaling through the CD3 complex

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Profound block in thymocyte development in mice lacking p56lck

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

CD69 expression during selection and maturation of CD4+8+ thymocytes.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

T cell development in mice that lack the zeta chain of the T cell antigen receptor complex

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Early stages in human and mouse T-cell development

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Over-expression of CD3 epsilon transgenes blocks T lymphocyte development.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

A signal strength hypothesis of thymic selection: preliminary considerations

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

T cell development in mice lacking the CD3-zeta/eta gene.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Regulation of thymocyte development through CD3. II. Expression of T cell receptor beta CD3 epsilon and maturation to the CD4+8+ stage are highly correlated in individual thymocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Regulation of thymocyte development through CD3. I. Timepoint of ligation of CD3 epsilon determines clonal deletion or induction of developmental program

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Signal transduction by lymphocyte antigen receptors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Double-negative thymocyte subsets in CD3′ chain-deficient mice: Absence of HSA+CD44−CD25− cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Signaling mechanisms in thymocyte selection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Evidence for a differential avidity model of T cell selection in the thymus

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

T cell receptor antagonist peptides induce positive selection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(95)90091-8

Identifiers

DOI

10.1016/1074-7613(95)90091-8

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27 April 2018

PubMed ID

7648394

1 reference

27 April 2018