(Q52537650)

English

BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene.

scientific article published in December 1999

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scholarly article

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene. (English)

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

author name string

Snouwaert JN

1

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

Gowen LC

2

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

Latour AM

3

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

Mohn AR

4

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

Xiao A

5

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

DiBiase L

6

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

Koller BH

7

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

language of work or name

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publication date

1 December 1999

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

18

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

7900-7907

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

55

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203334

0 references

Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Isolation of the murine Nbr1 gene adjacent to the murine Brca1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

BRCA1 required for transcription-coupled repair of oxidative DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Loss of heterozygosity induced by a chromosomal double-strand break

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Cotransformation and gene targeting in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Double-strand break repair by interchromosomal recombination: suppression of chromosomal translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Efficient gene targeting in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

Transcriptional activation by BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

21 January 2018

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

7 January 2021

based on heuristic

inferred from DOI database lookup

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

7 January 2021

based on heuristic

inferred from DOI database lookup

The many interfaces of Mre11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine Brca1: sequence and significance for human missense mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of Brca1 deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203334

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1203334

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

release_k2cofu73qndvxoosmbbnsezf2m

1 reference

https://api.fatcat.wiki/v0/release/k2cofu73qndvxoosmbbnsezf2m

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

2 May 2018

http://europepmc.org/abstract/MED/10630642

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