(Q52666716)

5 May 2018

review article

1 reference

title

High-throughput RNAi screening in cultured cells: a user's guide. (English)

1 reference

5 May 2018

author

Norbert Perrimon

series ordinal

2

1 reference

5 May 2018

author name string

Christophe J Echeverri

series ordinal

1

1 reference

5 May 2018

publication date

1 May 2006

1 reference

5 May 2018

published in

Nature Reviews Genetics

1 reference

5 May 2018

volume

7

1 reference

5 May 2018

page(s)

373-384

1 reference

5 May 2018

issue

5

1 reference

5 May 2018

https://scigraph.springernature.com/pub.10.1038/nrg1836

exact match

0 references

cites work

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

21 January 2018

1 reference

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

21 January 2018

1 reference

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

21 January 2018

1 reference

A species of small antisense RNA in posttranscriptional gene silencing in plants

21 January 2018

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

Systematic genome-wide screens of gene function

21 January 2018

1 reference

Functional genomics to new drug targets

21 January 2018

1 reference

A functional genomic analysis of cell morphology using RNA interference

21 January 2018

1 reference

Genome-wide RNAi analysis of growth and viability in Drosophila cells

21 January 2018

1 reference

Genome-wide survey of protein kinases required for cell cycle progression.

21 January 2018

1 reference

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

21 January 2018

1 reference

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

21 January 2018

1 reference

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

21 January 2018

1 reference

Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila

21 January 2018

1 reference

Identification of JAK/STAT signalling components by genome-wide RNA interference.

21 January 2018

1 reference

Functional dissection of an innate immune response by a genome-wide RNAi screen

21 January 2018

1 reference

An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila.

21 January 2018

1 reference

Functional genomic analysis of the Wnt-wingless signaling pathway

21 January 2018

1 reference

Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition

21 January 2018

1 reference

Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection

21 January 2018

1 reference

Genome-wide RNAi screen for host factors required for intracellular bacterial infection

21 January 2018

1 reference

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

21 January 2018

1 reference

A resource for large-scale RNA-interference-based screens in mammals.

21 January 2018

1 reference

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity

21 January 2018

1 reference

A genetic screen for candidate tumor suppressors identifies REST

21 January 2018

1 reference

Design of a genome-wide siRNA library using an artificial neural network

21 January 2018

1 reference

A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function

21 January 2018

1 reference

Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

21 January 2018

1 reference

An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

21 January 2018

1 reference

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

21 January 2018

1 reference

High-throughput RNA interference screens in Drosophila tissue culture cells.

21 January 2018

1 reference

Newly established cell lines from Drosophila larval CNS express neural specific characteristics

21 January 2018

1 reference

Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages

21 January 2018

1 reference

The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis

21 January 2018

1 reference

High-throughput RNAi screening in vitro: from cell lines to primary cells.

21 January 2018

1 reference

Rational siRNA design for RNA interference

21 January 2018

1 reference

Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference

21 January 2018

1 reference

Small interfering RNA-mediated gene silencing in T lymphocytes

21 January 2018

1 reference

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

21 January 2018

1 reference

Second-generation shRNA libraries covering the mouse and human genomes

21 January 2018

1 reference

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 January 2018

1 reference

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

21 January 2018

1 reference

Microarrays of cells expressing defined cDNAs

21 January 2018

1 reference

RNAi microarray analysis in cultured mammalian cells

21 January 2018

1 reference

RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells

21 January 2018

1 reference

RNAi living-cell microarrays for loss-of-function screens in Drosophila melanogaster cells.

21 January 2018

1 reference

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

21 January 2018

1 reference

siRNAs can function as miRNAs

21 January 2018

1 reference

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

21 January 2018

1 reference

Activation of the mammalian immune system by siRNAs.

21 January 2018

1 reference

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

Microarrays of lentiviruses for gene function screens in immortalized and primary cells

21 January 2018

1 reference

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

21 January 2018

1 reference

In situ fluorescence analysis demonstrates active siRNA exclusion from the nucleus by Exportin 5.

21 January 2018

1 reference

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

1 reference

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

21 January 2018

1 reference

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

Nuclear export of microRNA precursors

21 January 2018

1 reference

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

21 January 2018

1 reference

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

1 reference

Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

21 January 2018

1 reference

Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

21 January 2018

1 reference

Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

1 reference

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

21 January 2018

1 reference

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

21 January 2018

1 reference

Genes required for Drosophila nervous system development identified by RNA interference.

21 January 2018

1 reference

Identification and characterization of a novel line of Drosophila Schneider S2 cells that respond to wingless signaling

21 January 2018

1 reference

In vitro culture of Drosophila melanogaster embryonic cells.

21 January 2018

1 reference

The ultrastructure of imaginal disc cells in primary cultures and during cell aggregation in continuous cell lines

21 January 2018

1 reference

RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells

21 January 2018

1 reference

siRNA cell arrays for high-content screening microscopy

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1836

1 reference

5 May 2018

PubMed ID

16607398

1 reference

5 May 2018