(Q53235986)

12 May 2018

title

Alzheimer's disease. Closing in on gamma-secretase. (English)

1 reference

12 May 2018

author name string

De Strooper B

series ordinal

1

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12 May 2018

language of work or name

English

0 references

publication date

1 June 2000

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12 May 2018

published in

Nature

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12 May 2018

volume

405

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12 May 2018

page(s)

627, 629

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12 May 2018

issue

6787

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12 May 2018

https://scigraph.springernature.com/pub.10.1038/35015193

exact match

0 references

cites work

Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

1 reference

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

1 reference

Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

1 reference

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

1 reference

Mapping the Hawaiian plume conduit with converted seismic waves

21 January 2018

1 reference

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

1 reference

The presenilins in Alzheimer's disease--proteolysis holds the key.

21 January 2018

1 reference

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

21 January 2018

1 reference

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

1 reference

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/35015193

1 reference

12 May 2018

Dimensions Publication ID

0 references

1 reference

12 May 2018