(Q53361783)

13 May 2018

title

Jak/Stat3 signaling promotes somatic cell reprogramming by epigenetic regulation. (English)

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13 May 2018

author name string

Yong Tang

1

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13 May 2018

Yan Luo

2

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13 May 2018

Zongliang Jiang

3

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13 May 2018

Yinghong Ma

4

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13 May 2018

Chih-Jen Lin

5

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13 May 2018

Chul Kim

6

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13 May 2018

Mark G Carter

7

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13 May 2018

Tomokazu Amano

8

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13 May 2018

Joonghong Park

9

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13 May 2018

Sharon Kish

10

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13 May 2018

Xiuchun Cindy Tian

11

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13 May 2018

publication date

1 December 2012

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13 May 2018

published in

Stem Cells

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13 May 2018

volume

30

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13 May 2018

page(s)

2645-2656

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13 May 2018

issue

12

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13 May 2018

Generation of germline-competent induced pluripotent stem cells

cites work

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Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

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Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

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Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency

21 January 2018

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Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

21 January 2018

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Reprogramming of mouse and human cells to pluripotency using mature microRNAs.

21 January 2018

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Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

21 January 2018

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Generation of induced pluripotent stem cells using recombinant proteins

21 January 2018

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Stable transmission of reversible modifications: maintenance of epigenetic information through the cell cycle

21 January 2018

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Nuclear reprogramming in mouse primordial germ cells: epigenetic contribution.

21 January 2018

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Epigenetic reprogramming and induced pluripotency

21 January 2018

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Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

21 January 2018

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In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

21 January 2018

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Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

21 January 2018

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Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells

21 January 2018

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Dissecting direct reprogramming through integrative genomic analysis

21 January 2018

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Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

21 January 2018

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Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

21 January 2018

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DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction

21 January 2018

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Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L.

21 January 2018

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Dynamic instability of genomic methylation patterns in pluripotent stem cells

21 January 2018

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Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

21 January 2018

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A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

21 January 2018

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Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling.

21 January 2018

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Signalling, cell cycle and pluripotency in embryonic stem cells

21 January 2018

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Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

21 January 2018

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Gp130 and the interleukin-6 family of cytokines

21 January 2018

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STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

21 January 2018

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Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.

21 January 2018

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LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism.

21 January 2018

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The ground state of embryonic stem cell self-renewal

21 January 2018

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JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency

21 January 2018

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Stat3 activation is limiting for reprogramming to ground state pluripotency.

21 January 2018

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21 January 2018

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Signaling mechanisms regulating self-renewal and differentiation of pluripotent embryonic stem cells.

21 January 2018

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SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

21 January 2018

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Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

21 January 2018

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Nanog is the gateway to the pluripotent ground state.

21 January 2018

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Direct reprogramming of mouse fibroblasts to neural progenitors

21 January 2018

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Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage

21 January 2018

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Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

21 January 2018

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DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity

21 January 2018

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Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing

21 January 2018

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The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

21 January 2018

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The role of DNA hypermethylation and demethylation in cancer and cancer therapy

21 January 2018

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AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability

21 January 2018

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Identification of novel direct Stat3 target genes for control of growth and differentiation

21 January 2018

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

21 January 2018

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Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

21 January 2018

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Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

21 January 2018

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Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development

21 January 2018

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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

21 January 2018

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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

21 January 2018

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Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function

21 January 2018

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Concise review: Deciphering the mechanism behind induced pluripotent stem cell generation

21 January 2018

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The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells

21 January 2018

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A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog

21 January 2018

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myc maintains embryonic stem cell pluripotency and self-renewal

21 January 2018

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c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

21 January 2018

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

21 January 2018

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Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L

21 January 2018

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Dnmt3L and the establishment of maternal genomic imprints.

21 January 2018

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

21 January 2018

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Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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Reprogramming of human somatic cells to pluripotency with defined factors

21 January 2018

1 reference

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

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DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination

21 January 2018

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Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells

21 January 2018

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Direct cell reprogramming is a stochastic process amenable to acceleration

21 January 2018

1 reference

Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues

21 January 2018

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Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state

21 January 2018

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Regulation of somatic cell reprogramming through inducible mir-302 expression

21 January 2018

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Progress in understanding reprogramming to the induced pluripotent state

21 January 2018

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Core transcriptional regulatory circuitry in human embryonic stem cells

21 January 2018

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The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

21 January 2018

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Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

21 January 2018

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1225

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13 May 2018

PubMed ID

22968989

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13 May 2018