(Q53407295)

14 May 2018

title

Cooperative transformation of 32D cells by the combined expression of IRS-1 and V-Ha-Ras. (English)

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14 May 2018

author name string

B Cristofanelli

1

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14 May 2018

B Valentinis

2

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14 May 2018

S Soddu

3

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14 May 2018

M G Rizzo

4

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14 May 2018

A Marchetti

5

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14 May 2018

G Bossi

6

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14 May 2018

A R Morena

7

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14 May 2018

M Dews

8

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14 May 2018

R Baserga

9

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14 May 2018

A Sacchi

10

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14 May 2018

language of work or name

English

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publication date

1 July 2000

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14 May 2018

published in

Oncogene

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14 May 2018

volume

19

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14 May 2018

page(s)

3245-3255

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14 May 2018

issue

29

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14 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203664

exact match

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cites work

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

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Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

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The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.

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Interference with p53 protein inhibits hematopoietic and muscle differentiation

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Wild-type p53 induces diverse effects in 32D cells expressing different oncogenes.

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Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression

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Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules

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Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion

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IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells

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The IRS-signalling system: a network of docking proteins that mediate insulin action

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The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis

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Co-operation of simian virus 40 T antigen and insulin receptor substrate-1 in protection from apoptosis induced by interleukin-3 withdrawal

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Human skeletal muscle insulin receptor substrate-1. Characterization of the cDNA, gene, and chromosomal localization

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7 January 2021

The IGF-I receptor in cell growth, transformation and apoptosis.

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7 January 2021

IRS-1 is a common element in insulin and insulin-like growth factor-I signaling to the phosphatidylinositol 3'-kinase

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7 January 2021

Growth and differentiation signals by the insulin-like growth factor 1 receptor in hemopoietic cells are mediated through different pathways

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203664

1 reference

14 May 2018

Dimensions Publication ID

0 references

1 reference

14 May 2018