(Q53563511)

15 May 2018

title

Eotaxin selectively binds heparin. An interaction that protects eotaxin from proteolysis and potentiates chemotactic activity in vivo. (English)

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15 May 2018

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Julia I Ellyard

1

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15 May 2018

Ljubov Simson

2

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15 May 2018

Anna Bezos

3

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15 May 2018

Kellie Johnston

4

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15 May 2018

Craig Freeman

5

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15 May 2018

Christopher R Parish

6

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15 May 2018

language of work or name

English

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publication date

23 March 2007

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15 May 2018

Journal of Biological Chemistry

published in

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15 May 2018

volume

282

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15 May 2018

page(s)

15238-15247

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15 May 2018

issue

20

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15 May 2018

Regulation of protein function by glycosaminoglycans--as exemplified by chemokines

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A kinetics and modeling study of RANTES(9-68) binding to heparin reveals a mechanism of cooperative oligomerization

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Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8.

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Cell surface heparan sulfate proteoglycans: selective regulators of ligand-receptor encounters

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Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV.

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Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines

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Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation

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The chemokine, eotaxin, activates guinea-pig eosinophils in vitro and causes their accumulation into the lung in vivo.

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Murine eotaxin: an eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression

21 January 2018

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Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils

21 January 2018

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Cloning, expression, and characterization of the human eosinophil eotaxin receptor

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Plasminogen is tethered with high affinity to the cell surface by the plasma protein, histidine-rich glycoprotein

21 January 2018

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Human platelet heparanase: purification, characterization and catalytic activity

21 January 2018

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Isolation and characterization of cell adhesion molecules from the marine sponge, Ophlitaspongia tenuis.

21 January 2018

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Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice

21 January 2018

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Interaction of chemokines and glycosaminoglycans: a new twist in the regulation of chemokine function with opportunities for therapeutic intervention

21 January 2018

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Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation

21 January 2018

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Structural and functional analysis of the RANTES-glycosaminoglycans interactions

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of chondroitin sulfate E proteoglycans and heparin proteoglycans in the secretory granules of human lung mast cells

21 January 2018

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Mast cell beta-tryptase selectively cleaves eotaxin and RANTES and abrogates their eosinophil chemotactic activities.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Effects of inhaled low molecular weight heparin on airway allergic inflammation in aerosol-ovalbumin-sensitized guinea pigs.

21 January 2018

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Heparin inhibits allergen-induced eosinophil infiltration into guinea-pig lung via a mechanism unrelated to its anticoagulant activity.

21 January 2018

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Inhibition of antigen-induced acute bronchoconstriction, airway hyperresponsiveness, and mast cell degranulation by a nonanticoagulant heparin: comparison with a low molecular weight heparin.

21 January 2018

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Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process.

21 January 2018

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21 January 2018

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Glycosaminoglycans Mediate Cell Surface Oligomerization of Chemokines

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M608046200

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15 May 2018

PubMed ID

17384413

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15 May 2018