(Q54147751)

25 May 2018

title

Furin-mediated cleavage of Pseudomonas exotoxin-derived chimeric toxins. (English)

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25 May 2018

author name string

Chiron MF

series ordinal

1

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25 May 2018

Fryling CM

series ordinal

2

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25 May 2018

FitzGerald D

series ordinal

3

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25 May 2018

language of work or name

English

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publication date

1 December 1997

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25 May 2018

Journal of Biological Chemistry

published in

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25 May 2018

volume

272

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25 May 2018

page(s)

31707-31711

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25 May 2018

issue

50

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25 May 2018

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

The exotoxin of P. Aeruginosa: A proenzyme having an unusual mode of activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Pseudomonas exotoxin-mediated selection yields cells with altered expression of low-density lipoprotein receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Recombinant toxins: new therapeutic agents for cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Pseudomonas exotoxin exhibits increased sensitivity to furin when sequences at the cleavage site are mutated to resemble the arginine-rich loop of diphtheria toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Furin-induced cleavage and activation of Shiga toxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

Recombinant RFB4 single-chain immunotoxin that is cytotoxic towards CD22-positive cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.50.31707

21 January 2018

Identifiers

DOI

10.1074/JBC.272.50.31707

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25 May 2018

PubMed ID

9395513

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25 May 2018