(Q54537089)

English

The cyclin-dependent kinase inhibitor roscovitine inhibits kinase activity, cell proliferation, multicellular development, and Cdk5 nuclear translocation in Dictyostelium discoideum.

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

The cyclin-dependent kinase inhibitor roscovitine inhibits kinase activity, cell proliferation, multicellular development, and Cdk5 nuclear translocation in Dictyostelium discoideum. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

Dictyostelium discoideum

0 references

multicellularity

1 reference

based on heuristic

inferred from title

author name string

Robert J Huber

1

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

Danton H O'Day

2

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

publication date

1 March 2012

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

Journal of Cellular Biochemistry

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

113

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

3

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

868-876

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

Expression analysis and molecular targeting of cyclin-dependent kinases in advanced melanoma

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Antiviral activity of CYC202 in HIV-1-infected cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Roscovitine targets, protein kinases and pyridoxal kinase

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

A decade of CDK5.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Roscovitine inhibits activation of promoters in herpes simplex virus type 1 genomes independently of promoter-specific factors

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Novel insights into the beneficial and detrimental actions of cdk5.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Roscovitine regulates invasive breast cancer cell (MDA-MB231) proliferation and survival through cell cycle regulatory protein cdk5.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Targets downstream of Cdk8 in Dictyostelium development

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

EGF-like peptide-enhanced cell motility in Dictyostelium functions independently of the cAMP-mediated pathway and requires active Ca2+/calmodulin signaling.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Design, synthesis, and testing of an 6-O-linked series of benzimidazole based inhibitors of CDK5/p25.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Regulation of NMDA receptors by cyclin-dependent kinase-5

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Cyclin-dependent kinase 5 regulates endothelial cell migration and angiogenesis.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

A homologue of Cdk8 is required for spore cell differentiation in Dictyostelium

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Cyclin B and Cdc2 expression and Cd2 kinase activity during Dictyostelium differentiation.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Isolation and characterization of a cdc 2 cDNA from Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

The isolation from a unicellular organism, Dictyostelium discoideum, of a highly-related cdc2 gene with characteristics of the PCTAIRE subfamily

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Nucleomorphin. A novel, acidic, nuclear calmodulin-binding protein from dictyostelium that regulates nuclear number

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Phosphorylation of human high molecular weight neurofilament protein (hNF-H) by neuronal cyclin-dependent kinase 5 (cdk5)

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Dictyostelium Hip1r contributes to spore shape and requires epsin for phosphorylation and localization.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Extraneuronal roles of cyclin-dependent kinase 5.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

dictyExpress: a Dictyostelium discoideum gene expression database with an explorative data analysis web-based interface.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Cdk5 regulates the organization of Nestin and its association with p35

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Binding and catalytic properties of the Cdc2 and Crp proteins of Dictyostelium

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Four distinct cyclin-dependent kinases phosphorylate histone H1 at all of its growth-related phosphorylation sites

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

A novel Dictyostelium Cdk8 is required for aggregation, but is dispensable for growth.

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Cdk5 and MAPK are associated with complexes of cytoskeletal proteins in rat brain

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-α in human ER-positive breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Interference with ER-α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER-positive breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

The cell cycle and its relationship to development in Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1002%2FJCB.23417

21 January 2018

Identifiers

10.1002/JCB.23417

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 May 2018

http://europepmc.org/abstract/MED/22234985

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q54537089&oldid=1548537315"