(Q55216617)

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Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent

scientific article published on 26 April 2010

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26 June 2018

Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

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Alexander W Krug

1

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26 June 2018

Lena Allenhöfer

2

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Europe PubMed Central

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26 June 2018

Robert Monticone

3

1 reference

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26 June 2018

Michael Gekle

5

1 reference

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26 June 2018

Mingyi Wang

6

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26 June 2018

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26 April 2010

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26 June 2018

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

55

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Europe PubMed Central

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26 June 2018

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

1476-1483

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

Milk fat globule protein epidermal growth factor-8: a pivotal relay element within the angiotensin II and monocyte chemoattractant protein-1 signaling cascade mediating vascular smooth muscle cells invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Arterial aging and subclinical arterial disease are fundamentally intertwined at macroscopic and molecular levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Aldosterone and metabolic syndrome: is increased aldosterone in metabolic syndrome patients an additional risk factor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

A lifetime of aldosterone excess: long-term consequences of altered regulation of aldosterone production for cardiovascular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Nongenotropic aldosterone effects and the EGFR: interaction and biological relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Aldosterone and vascular inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Dehydroepiandrosterone induces a neuroendocrine phenotype in nerve growth factor-stimulated chromaffin pheochromocytoma PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Human adipocytes induce an ERK1/2 MAP kinases-mediated upregulation of steroidogenic acute regulatory protein (StAR) and an angiotensin II-sensitization in human adrenocortical cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Minireview: aldosterone and the cardiovascular system: genomic and nongenomic effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Effects of aldosterone on the vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Arterial aging: is it an immutable cardiovascular risk factor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Effect of aldosterone and mineralocorticoid receptor blockade on vascular inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

The future of aging therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Rat aortic MCP-1 and its receptor CCR2 increase with age and alter vascular smooth muscle cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Aldosterone stimulates epidermal growth factor receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Mineralocorticoid receptors and pathophysiological roles for aldosterone in the cardiovascular system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Vascular smooth muscle cell cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Development of animal models of aging at the national institute on aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

30 June 2018

Arterial aging is risky

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Aldosterone nongenomically produces NADPH oxidase-dependent reactive oxygen species and induces myocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

EF domains are sufficient for nongenomic mineralocorticoid receptor actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Association of adrenal steroids with hypertension and the metabolic syndrome in blacks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Plasma aldosterone is independently associated with the metabolic syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

The metabolic syndrome in older individuals: prevalence and prediction of cardiovascular events: the Cardiovascular Health Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Do human vascular endothelial cells produce aldosterone?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Increased carotid wall elastic modulus and fibronectin in aldosterone-salt-treated rats: effects of eplerenone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Human epidermal growth factor receptor-1 expression renders Chinese hamster ovary cells sensitive to alternative aldosterone signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883813

13 August 2018

Aldosterone: a mediator of myocardial necrosis and renal arteriopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of aldosterone in isolated rat blood vessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of aldosterone synthase in human vascular endothelial cells by angiotensin II and adrenocorticotropin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of the arterial internal elastic lamina by inhibition of the renin-angiotensin system in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix Metalloproteinase 2 Activation of Transforming Growth Factor-β1 (TGF-β1) and TGF-β1–Type II Receptor Signaling Within the Aged Arterial Wall

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinflammatory Profile Within the Grossly Normal Aged Human Aortic Wall

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aortic aging in the Fischer 344 / NNiaHSd x Brown Norway / BiNia Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421514

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/HYPERTENSIONAHA.109.148783

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20421514%20AND%20SRC:MED&resulttype=core&format=json

26 June 2018

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