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Antibody engineering
scientific article published on 01 April 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Antibody engineering
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
M S Hayden
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
L K Gilliland
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
J A Ledbetter
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
language of work or name
English
0 references
publication date
1 April 1997
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
201-212
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
3 Protein engineering of single-chain Fv analogs and fusion proteins
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An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.
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"Diabodies": small bivalent and bispecific antibody fragments
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Properties of a single-chain antibody containing different linker peptides.
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Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
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Cloning immunoglobulin variable domains for expression by the polymerase chain reaction
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Rapid and reliable cloning of antibody variable regions and generation of recombinant single chain antibody fragments
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Isolation of high affinity human antibodies directly from large synthetic repertoires.
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7 January 2021
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Selection and evolution of high-affinity human anti-viral antibodies
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Clonal selection and amplification of phage displayed antibodies by linking antigen recognition and phage replication
1 reference
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Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library
1 reference
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7 January 2021
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A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities
1 reference
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7 January 2021
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Surface expression of CD28 single chain Fv for costimulation by tumor cells
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Targeted therapy of carcinomas using BR96 sFv-PE40, a single-chain immunotoxin that binds to the Le(y) antigen
1 reference
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7 January 2021
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Engineering antibody Fv fragments for cancer detection and therapy: disulfide-stabilized Fv fragments.
1 reference
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7 January 2021
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Toward the production of bispecific antibody fragments for clinical applications
1 reference
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A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
1 reference
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G-CSF-stimulated PMN in immunotherapy of breast cancer with a bispecific antibody to Fc gamma RI and to HER-2/neu (MDX-210).
1 reference
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Alternative triggering molecules and single chain bispecific antibodies
1 reference
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Crossref
reference URL
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7 January 2021
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Engineering disulfide-linked single-chain Fv dimers [(sFv')2] with improved solution and targeting properties: anti-digoxin 26-10 (sFv')2 and anti-c-erbB-2 741F8 (sFv')2 made by protein folding and bonded through C-terminal cysteinyl peptides
1 reference
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Engineering high affinity humanized anti-p185HER2/anti-CD3 bispecific F(ab')2 for efficient lysis of p185HER2 overexpressing tumor cells
1 reference
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7 January 2021
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Costimulation by CD28 sFv expressed on the tumor cell surface or as a soluble bispecific molecule targeted to the L6 carcinoma antigen.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
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A single-chain bispecific Fv2 molecule produced in mammalian cells redirects lysis by activated CTL.
1 reference
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Crossref
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Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody
1 reference
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Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody
1 reference
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7 January 2021
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Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody
1 reference
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Intracellular single chain Fv antibody inhibits Ras activity in T-cell antigen receptor stimulated Jurkat cells
1 reference
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Crossref
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7 January 2021
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Targeted tumor killing via an intracellular antibody against erbB-2.
1 reference
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Crossref
reference URL
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Intracellular immunization: antibody targeting to subcellular compartments
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Intracellular immunization with cytosolic recombinant antibodies.
1 reference
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Crossref
reference URL
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7 January 2021
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Cleavable CD40Ig fusion proteins and the binding to sgp39.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
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inferred from DOI database lookup
Production of monoclonal antibodies in COS and CHO cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
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Humanization of a mouse monoclonal antibody by CDR–grafting: the importance of framework residues on loop conformation
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Combined intra- and extracellular immunization against human immunodeficiency virus type 1 infection with a human anti-gp120 antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
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Humanization of murine monoclonal antibodies through variable domain resurfacing
1 reference
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Crossref
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7 January 2021
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Conversion of murine Fabs isolated from a combinatorial phage display library to full length immunoglobulins
1 reference
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7 January 2021
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Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system
1 reference
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Crossref
reference URL
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7 January 2021
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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
1 reference
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Crossref
reference URL
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7 January 2021
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Polymerase chain reaction facilitates the cloning, CDRgrafting, and rapid expression of a murine monoclonal antibody directed against the CD18 component of leukocyte integrins
1 reference
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reference URL
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1 reference
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reference URL
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Selection and coamplification of heterologous genes in mammalian cells
1 reference
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Crossref
reference URL
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7 January 2021
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High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker
1 reference
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Crossref
reference URL
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7 January 2021
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In pursuit of the optimal fed-batch process for monoclonal antibody production
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
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Optimizing antibody production in batch hybridoma cell culture
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
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Protein folding in vivo and renaturation of recombinant proteins from inclusion bodies
1 reference
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7 January 2021
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High-level production of a functional immunoglobulin heterodimer in a baculovirus expression system
1 reference
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Crossref
reference URL
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7 January 2021
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Baculovirus expression of a functional single-chain immunoglobulin and its IL-2 fusion protein
1 reference
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Crossref
reference URL
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7 January 2021
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Heavy chain dimers as well as complete antibodies are efficiently formed and secreted from Drosophila via a BiP-mediated pathway
1 reference
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Crossref
reference URL
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7 January 2021
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Generation and assembly of secretory antibodies in plants
1 reference
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reference URL
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7 January 2021
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Intracellular antibodies: development and therapeutic potential.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Humanized antibodies: enhancing therapeutic utility through antibody engineering
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protein engineering techniques for antibody humanization
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of framework residues required to restore antigen binding during reshaping of a monoclonal antibody against the glycoprotein gB of human cytomegalovirus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reshaping human antibodies for therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody framework residues affecting the conformation of the hypervariable loops
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
A combinatorial library strategy for the rapid humanization of anticarcinoma BR96 Fab.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phage display: protein engineering by directed evolution
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Domain libraries: synthetic diversity for de novo design of antibody V-regions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
A new phage display system to construct multicombinatorial libraries of very large antibody repertoires
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
By-passing immunization: building high affinity human antibodies by chain shuffling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic human antibodies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selection of phage-displayed antibodies specific for a cytoskeletal antigen by competitive elution with a monoclonal antibody
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristics of human antibody repertoires following active immune responses in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen-specific human antibodies from mice comprising four distinct genetic modifications
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human antibodies from transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of fully human antibodies by transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germ-line transmission and expression of a human-derived yeast artificial chromosome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Strategies for expressing human antibody repertoires in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the structural integrity of YACs comprising human immunoglobulin genes in yeast and in embryonic stem cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A repertoire of monoclonal antibodies with human heavy chains from transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human immunoglobulin transgenes undergo rearrangement, somatic mutation and class switching in mice that lack endogenous IgM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro immunization of naive human B cells yields high affinity immunoglobulin G antibodies as illustrated by phage display
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombination of a mixture of univalent antibody fragments of different specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bispecific monoclonal antibodies from hybrid hybridomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of apoptosis in bispecific antibody-mediated T-cell cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phage diabody repertoires for selection of large numbers of bispecific antibody fragments
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tetravalent miniantibodies with high avidity assembling in Escherichia coli.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Leucine zipper dimerized bivalent and bispecific scFv antibodies from a semi-synthetic antibody phage display library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A general route to fingerprint analyses of peptide-antibody interactions using a clustered amino acid peptide library: comparison with a phage display library
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Probing the basis of antibody reactivity with a panel of constrained peptide libraries displayed by filamentous phage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A complementarity-determining region synthetic peptide acts as a miniantibody and neutralizes human immunodeficiency virus type 1 in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small peptides as potent mimetics of the protein hormone erythropoietin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2897%2980136-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(97)80136-7
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed ID
9099794
1 reference
stated in
Europe PubMed Central
PubMed ID
9099794
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9099794%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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