(Q57315787)

1

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Marjolijn T. Merema

2

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Geny M.M. Groothuis

4

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Elisabeth Verpoorte

Biotechnology and Bioengineering

5

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publication date

27 January 2011

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published in

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volume

108

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issue

6

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page(s)

1404-1412

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cites work

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An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

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Efficient analysis of hepatic glucose output and insulin action using a liver slice culture system

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Precision-cut tissue slices as a tool to predict metabolism of novel drugs.

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Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies.

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Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices

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In vitro methods to study chemically-induced hepatotoxicity: a literature review

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Stability of Phase II Conjugation Systems in Cultured Precision-cut Rat Hepatic Slices

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Novel intra-tissue perfusion system for culturing thick liver tissue.

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Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors.

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Sulfotransferase gene expression in primary cultures of rat hepatocytes.

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Protection of liver cells from ethanol cytotoxicity by curcumin in liver slice culture in vitro

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Gene expression profiling of extracellular matrix as an effector of human hepatocyte phenotype in primary cell culture

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Glucuronidation of 4-methylumbelliferone and 4-hydroxybiphenyl and in vitro induction of UDP-glucuronosyltransferase 2B12-mRNA in precision-cut rat liver slices

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Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

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A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

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Morphological and functional integrity of precision-cut rat liver slices in rotating organ culture and multiwell plate culture: effects of oxygen tension

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Effect of dexamethasone treatment on the expression and function of transport proteins in sandwich-cultured rat hepatocytes

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Liver slices as a model to study fibrogenesis and test the effects of anti-fibrotic drugs on fibrogenic cells in human liver.

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Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies

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On-line HPLC analysis system for metabolism and inhibition studies in precision-cut liver slices.

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Organ slice viability extended for pathway characterization: an in vitro model to investigate fibrosis

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