(Q57316195)

English

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

article by Snaevar Sigurdsson et al published 6 December 2007 in Human Molecular Genetics

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scholarly article

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Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus (English)

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systemic lupus erythematosus

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based on heuristic

inferred from title

Snaevar Sigurdsson

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Snaevar Sigurdsson

1

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Johanna Sandling

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Johanna K. Sandling

6

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object named as

Lili Milani

4

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Elisabet Svenungsson

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Elisabet Svenungsson

11

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Ann-Christine Syvänen

18

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Ann-Christine Syvänen

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Maija-Leena Eloranta

7

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Maija-Leena Eloranta

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Andreas Jönsen

13

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Andreas Jönsen

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10

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Iva Gunnarsson

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Gunnel Nordmark

5

object named as

Gunnel Nordmark

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Gunnar Sturfelt

12

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Gunnar Sturfelt

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17

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Lars Rönnblom

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Lennart Truedsson

14

object named as

Lennart Truedsson

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author name string

Harald H.H. Göring

2

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Gudlaug Kristjansdottir

3

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Di Feng

8

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Niquiche Sangster-Guity

9

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Betsy J. Barnes

15

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Gunnar Alm

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publication date

6 December 2007

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Human Molecular Genetics

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17

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872-881

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6

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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

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https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

The type I interferon system in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE).

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Mapping determinants of human gene expression by regional and genome-wide association

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Association of IRF5 in UK SLE families identifies a variant involved in polyadenylation

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Highly parallel SNP genotyping

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Estimating the Dimension of a Model

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

The Sp-family of transcription factors

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Activation of the RNA-dependent protein kinase PKR promoter in the absence of interferon is dependent upon Sp proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

The PKR kinase promoter binds both Sp1 and Sp3, but only Sp3 functions as part of the interferon-inducible complex with ISGF-3 proteins

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

The 1982 revised criteria for the classification of systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Elevated triglycerides and low levels of high-density lipoprotein as markers of disease activity in association with up-regulation of the tumor necrosis factor alpha/tumor necrosis factor receptor system in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Analysis of HLA DR, HLA DQ, C4A, FcgammaRIIa, FcgammaRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcgammaRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Multipoint quantitative-trait linkage analysis in general pedigrees

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Quantitative trait nucleotide analysis using Bayesian model selection.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Opposed independent effects and epistasis in the complex association of IRF5 to SLE

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDM359

21 January 2018

Identifiers

10.1093/HMG/DDM359

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