(Q57694760)

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Detection of point mutations in the p53 gene: Comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques

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Detection of point mutations in the p53 gene: Comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques (English)

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Rosalind Eeles

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Anne-Lise Børresen-Dale

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object named as

Anne-Lise Borresen

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author name string

Alison Condie

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Christopher Coles

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Colin Cooper

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Jane Prosser

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publication date

1993

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2

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58-66

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1

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Detection of single base changes in nucleic acids

1 reference

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Mutations in p53 do not account for heritable breast cancer: a study in five affected families

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Screening for mutations in human HPRT cDNA using the polymerase chain reaction (PCR) in combination with constant denaturant gel electrophoresis (CDGE)

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Diagnostic single strand conformational polymorphism, (SSCP): a simplified non-radioisotopic method as applied to a Tay-Sachs B1 variant

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Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations

1 reference

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Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations

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DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory

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p53 mutations in human cancers

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Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection

1 reference

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Computational simulation of DNA melting and its application to denaturing gradient gel electrophoresis

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Sequence-Determined DNA Separations

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[31] Detection and localization of single base changes by denaturing gradient gel electrophoresis

1 reference

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Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

1 reference

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Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

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DNA sequence polymorphisms in Alu repeats

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Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes

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based on heuristic

inferred from DOI database lookup

Protocols for an improved detection of point mutations by SSCP

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inferred from DOI database lookup

Comparison of RNase A, a chemical cleavage and GC-clamped denaturing gradient gel electrophoresis for the detection of mutations in exon 9 of the human acid beta-glucosidase gene

1 reference

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based on heuristic

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10.1002/HUMU.1380020111

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