(Q57976942)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Drug-stimulated ATPase activity of human P-glycoprotein requires movement between transmembrane segments 6 and 12 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

main subject

transmembrane protein

0 references

author

Tip W. Loo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

D M Clarke

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 August 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

20986-20989

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

Genetic analysis of the multidrug transporter

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

P-glycoprotein and multidrug resistance

21 January 2018

1 reference

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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Membrane topology of a cysteine-less mutant of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Mutational Analysis of the Predicted First Transmembrane Segment of Each Homologous Half of Human P-glycoprotein Suggests That They Are Symmetrically Arranged in the Membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Transmembrane organization of mouse P-glycoprotein determined by epitope insertion and immunofluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

The minimum functional unit of human P-glycoprotein appears to be a monomer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Covalent modification of human P-glycoprotein mutants containing a single cysteine in either nucleotide-binding fold abolishes drug-stimulated ATPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Mutations to amino acids located in predicted transmembrane segment 6 (TM6) modulate the activity and substrate specificity of human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Inhibition of Oxidative Cross-linking between Engineered Cysteine Residues at Positions 332 in Predicted Transmembrane Segments (TM) 6 and 975 in Predicted TM12 of Human P-glycoprotein by Drug Substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Alpha-helical protein assembly motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Alpha-helical coiled coils and bundles: how to design an alpha-helical protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Principles that determine the structure of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Specificity and promiscuity in membrane helix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

A method for the determination of inorganic phosphate in the presence of labile organic phosphate and high concentrations of protein: application to lens ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

Secondary and tertiary structure changes of reconstituted P-glycoprotein. A Fourier transform attenuated total reflection infrared spectroscopy analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.34.20986

21 January 2018

Identifiers

DOI

10.1074/JBC.272.34.20986

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9261097%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference