(Q58001211)

English

Regulation of Ras·GTP Loading and Ras-Raf Association in Neonatal Rat Ventricular Myocytes by G Protein-coupled Receptor Agonists and Phorbol Ester

scientific article published in Journal of Biological Chemistry

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scholarly article

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9 December 2019

Regulation of Ras.GTP loading and Ras-Raf association in neonatal rat ventricular myocytes by G protein-coupled receptor agonists and phorbol ester. Activation of the extracellular signal-regulated kinase cascade by phorbol ester is mediated by Ras (English)

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9 December 2019

G protein-coupled receptor

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based on heuristic

inferred from title

3

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9 December 2019

author name string

A Chiloeches

1

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9 December 2019

H F Paterson

2

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9 December 2019

A Clerk

4

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9 December 2019

C J Marshall

5

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9 December 2019

P H Sugden

6

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9 December 2019

language of work or name

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publication date

1 July 1999

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9 December 2019

Journal of Biological Chemistry

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9 December 2019

274

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9 December 2019

19762-19770

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9 December 2019

28

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9 December 2019

Increasing complexity of the Ras signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

The ins and outs of Raf kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Stimulation of phosphatidylinositol hydrolysis, protein kinase C translocation, and mitogen-activated protein kinase activity by bradykinin in rat ventricular myocytes: dissociation from the hypertrophic response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Insulin-like Growth Factor-I Rapidly Activates Multiple Signal Transduction Pathways in Cultured Rat Cardiac Myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Cell cycle-dependent activation of Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Quantitative analysis of the complex between p21ras and the Ras-binding domain of the human Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Activation of the mitogen-activated protein kinase cascade by pertussis toxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Improved mountant for immunofluorescence preparations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Dissociation of p44 and p42 mitogen-activated protein kinase activation from receptor-induced hypertrophy in neonatal rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Oncogenic src, raf, and ras stimulate a hypertrophic pattern of gene expression and increase cell size in neonatal rat ventricular myocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Stimulation of gene expression in neonatal rat ventricular myocytes by Ras is mediated by Ral guanine nucleotide dissociation stimulator (Ral.GDS) and phosphatidylinositol 3-kinase in addition to Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

The MEKK-JNK pathway is stimulated by alpha1-adrenergic receptor and ras activation and is associated with in vitro and in vivo cardiac hypertrophy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Interactions of protein kinase C with insulin signaling. Influence on GAP and Sos activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Involvement of p21ras in activation of extracellular signal-regulated kinase 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Activation of the MAP kinase pathway by the protein kinase raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

G(o)-protein alpha-subunits activate mitogen-activated protein kinase via a novel protein kinase C-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Negative regulation of Raf-1 by phosphorylation of serine 621.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Stimulation of p21 ras upon T-cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Regulation of RasGRP via a phorbol ester-responsive C1 domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.28.19762

21 January 2018

Identifiers

10.1074/JBC.274.28.19762

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391918%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10391918%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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