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Glucagon-like Peptide 1 (GLP-1): An Intestinal Hormone, Signalling Nutritional Abundance, with an Unusual Therapeutic Potential
scientific article published on 01 August 1999
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Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
title
Glucagon-like Peptide 1 (GLP-1): An Intestinal Hormone, Signalling Nutritional Abundance, with an Unusual Therapeutic Potential
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
author
Jens Juul Holst
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
publication date
1 August 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
published in
Trends in Endocrinology and Metabolism
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
volume
10
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
page(s)
229-235
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
cites work
Exon duplication and divergence in the human preproglucagon gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
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inferred from DOI database lookup
Hamster preproglucagon contains the sequence of glucagon and two related peptides.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
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inferred from DOI database lookup
Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
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The biological significance of "enteroglucagon." Present status
1 reference
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Crossref
reference URL
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7 January 2021
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Oxyntomodulin (glicentin-(33-69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
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Enteroglucagon
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
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Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Secretion of the Incretin Hormones Glucagon-Like Peptide-1 and Gastric Inhibitory Polypeptide Correlates with Insulin Secretion in Normal Man Throughout the Day
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ileal release of glucagon-like peptide-1 (GLP-1)
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Emptying of the gastric substitute, glucagon-like peptide-1 (GLP-1), and reactive hypoglycemia after total gastrectomy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastric emptying and release of incretin hormones after glucose ingestion in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide-1 7-36: a physiological incretin in man.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide-1 is a physiological incretin in rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1-(7-36) amide infused at near-physiological insulinotropic hormone and glucose concentrations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
In vitro insulinomimetic [corrected] effects of GLP-1 in liver, muscle and fat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Failure of GLP-1(7-36)amide to affect glycogenesis in rat skeletal muscle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of glucagon-like peptide-1 (7-36)amide on insulin stimulated rat skeletal muscle glucose transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GLP-1 does not acutely affect insulin sensitivity in healthy man
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide-1: a potent regulator of food intake in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for glucagon-like peptide-1 in the central regulation of feeding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Attenuated GLP-1 secretion in obesity: cause or consequence?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycation of glucagon-like peptide-1(7-36)amide: characterization and impaired action on rat insulin secreting cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-linkage of the glucagon-like peptide 1 receptor gene with maturity onset diabetes of the young
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gut incretin hormones in identical twins discordant for non-insulin-dependent diabetes mellitus (NIDDM)--evidence for decreased glucagon-like peptide 1 secretion during oral glucose ingestion in NIDDM twins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pathogenesis of NIDDM involves a defective expression of the GIP receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Near-normalisation of diurnal glucose concentrations by continuous administration of glucagon-like peptide-1 (GLP-1) in subjects with NIDDM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide-1 (GLP-1): a trial of treatment in non-insulin-dependent diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Release of glucagon-like peptide-1 (GLP-1) by carbohydrates in the perfused rat ileum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The U.K. Prospective Diabetes Study. A review.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1043-2760%2899%2900157-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1043-2760(99)00157-5
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
PubMed ID
10407397
1 reference
stated in
Europe PubMed Central
PubMed ID
10407397
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10407397%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 December 2019
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