(Q59172945)

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Second-sphere ‘communication’ between two cis-bound guanine nucleotides. Factors influencing conformations of dynamic adducts of cis-type platinum anticancer drugs with guanine nucleotides as deduced by circular dichroism spectroscopy

article published in 2000

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Second-sphere ‘communication’ between two cis-bound guanine nucleotides. Factors influencing conformations of dynamic adducts of cis-type platinum anticancer drugs with guanine nucleotides as deduced by circular dichroism spectroscopy (English)

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author name string

Hing C Wong

1

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Kazuo Shinozuka

2

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Giovanni Natile

3

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Luigi G Marzilli

4

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publication date

January 2000

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Inorganica Chimica Acta

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297

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36-46

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1-2

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Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities.

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NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin

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A Novel Head-to-Head Conformer of d(GpG) Cross-linked by Pt: New Light on the Conformation of Such Cross-links Formed by Pt Anticancer Drugs

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Retro Models of Pt Anticancer Drug DNA Adducts: Chirality-Controlling Chelate Ligand Restriction of Guanine Dynamic Motion in (2,2'-Bipiperidine)PtG(2) Complexes (G = Guanine Derivative)

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Chirality-Controlling Chelate (CCC) Ligands in Analogues of Platinum Anticancer Agents. Influence of N9 Substituents of Guanine Derivatives (G) on the Distribution of Chiral Conformers of (CCC)PtG(2) with CCC = N,N'-Dimethyl-2,3-diaminobutane

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Letter: The structure of (platinum(ethylenediamine)(guanosine)2)2+ cation

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Unusual hydrogen bonding patterns of N7metallated, N1deprotonated guanine nucleobases: acidity constants of cis-[Pt(NH3)2(Hegua)2]2+and crystal structures of cis-[Pt(NH3)2(egua)2]·4H2O and cis-[Pt(NH3)2(egua)2]· Hegua·7H2O (Hegua = 9-ethylguanine)

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Nuclear magnetic resonance studies of 5'-ribo- and deoxyribonucleotide structures in solution.

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H8 chemical shifts in oligonucleotide cross-linked at a GpG sequence by cis-Pt(NH3)2(2+): a clue to the adduct structure

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Extent of the Acidification by N7-Coordinated cis-Diammine-Platinum(II) on the Acidic Sites of Guanine Derivatives

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New Concepts Relevant to Cisplatin Anticancer Activity from Unique Spectral Features Providing Evidence That Adjacent Guanines in d(GpG), Intrastrand-Cross-Linked at N7 by acis-Platinum(II) Moiety, Can Adopt a Head-to-Tail Arrangement

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10.1016/S0020-1693(99)00256-X

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release_4uzr24mhnndd5jjfhmo7wprvmm

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