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p16INK4A and p19ARF act in overlapping pathways in cellular immortalization
scientific article published on 01 March 2000
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
title
p16INK4A and p19ARF act in overlapping pathways in cellular immortalization
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author
Amancio Carnero
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
J D Hudson
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
C M Price
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
D H Beach
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
publication date
1 March 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
published in
Nature Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
148-155
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/35004020
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Extension of life-span by introduction of telomerase into normal human cells
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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.
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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
1 reference
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Crossref
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7 January 2021
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The INK4a/ARF tumor suppressor: one gene--two products--two pathways
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7 January 2021
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7 January 2021
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Inhibition of ras-induced proliferation and cellular transformation by p16INK4.
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Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16
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Growth suppression by p16ink4 requires functional retinoblastoma protein
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7 January 2021
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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
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7 January 2021
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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
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7 January 2021
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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
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Interaction between the retinoblastoma protein and the oncoprotein MDM2
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E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis
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Role of the Rb/E2F pathway in cell growth control
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inferred from DOI database lookup
The retinoblastoma protein and cell cycle control
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stated in
Crossref
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Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia
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7 January 2021
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Identifiers
DOI
10.1038/35004020
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
PubMed ID
10707085
1 reference
stated in
Europe PubMed Central
PubMed ID
10707085
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10707085%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
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