(Q60678419)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8513845%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

title

Inhibition by paroxetine of desipramine metabolism in extensive but not in poor metabolizers of sparteine (English)

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13 October 2019

1

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13 October 2019

Søren H Sindrup

4

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13 October 2019

author name string

J G Hansen

2

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13 October 2019

K K Nielsen

3

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13 October 2019

L F Gram

5

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13 October 2019

publication date

1 January 1993

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European Journal of Clinical Pharmacology

13 October 2019

published in

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13 October 2019

volume

44

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13 October 2019

page(s)

349-355

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13 October 2019

issue

4

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https://scigraph.springernature.com/pub.10.1007/bf00316471

13 October 2019

exact match

0 references

cites work

Steady-state concentrations of imipramine and its metabolites in relation to the sparteine/debrisoquine polymorphism

1 reference

12 December 2020

Role of P450IID6, the target of the sparteine-debrisoquin oxidation polymorphism, in the metabolism of imipramine

1 reference

12 December 2020

Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

1 reference

12 December 2020

Fluoxetine and norfluoxetine are potent inhibitors of P450IID6--the source of the sparteine/debrisoquine oxidation polymorphism

1 reference

12 December 2020

The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine

1 reference

12 December 2020

Sparteine metabolism in Canadian Caucasians

1 reference

12 December 2020

An overview of the animal pharmacology of paroxetine

1 reference

12 December 2020

Enzyme induction in the cytochrome P-450 system

1 reference

12 December 2020

Citalopram: interaction studies with levomepromazine, imipramine, and lithium

1 reference

12 December 2020

S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin

1 reference

12 December 2020

Thioridazine effect on desipramine plasma levels

1 reference

12 December 2020

Imipramine demethylation and hydroxylation: impact of the sparteine oxidation phenotype

1 reference

12 December 2020

High-performance liquid chromatography of imipramine and six metabolites in human plasma and urine

1 reference

12 December 2020

Extremely slow metabolism of amitriptyline but normal metabolism of imipramine and desipramine in an extensive metabolizer of sparteine, debrisoquine, and mephenytoin

1 reference

12 December 2020

Quinidine inhibits the 2-hydroxylation of imipramine and desipramine but not the demethylation of imipramine

1 reference

12 December 2020

Inhibitors of imipramine metabolism by human liver microsomes

1 reference

12 December 2020

Imipramine metabolites in blood of patients during therapy and after overdose

1 reference

12 December 2020

Inhibition of desipramine 2-hydroxylation by quinidine and quinine

1 reference

12 December 2020

The genetic polymorphism of debrisoquine/sparteine metabolism--clinical aspects

1 reference

12 December 2020

Interaction between fluvoxamine and imipramine/desipramine in four patients

1 reference

12 December 2020

Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

1 reference

12 December 2020

Quantification and mechanism of the fluoxetine and tricyclic antidepressant interaction

1 reference

12 December 2020

The role of cytochrome P4502D6 in the metabolism of paroxetine by human liver microsomes

1 reference

12 December 2020

The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms

1 reference

12 December 2020

Interindividual variability in the N-sulphation of desipramine in human liver and platelets

1 reference

12 December 2020

The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes

1 reference

12 December 2020

The relationship between paroxetine and the sparteine oxidation polymorphism

1 reference

12 December 2020

Effects of perphenazine on imipramine metabolism in man

1 reference

12 December 2020

Fluoxetine induces elevation of desipramine level and exacerbation of geriatric nonpsychotic depression

1 reference

12 December 2020

Metabolism of tricyclic antidepressants. A review

1 reference

12 December 2020

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

1 reference

12 December 2020

Pharmacokinetics of the selective serotonin reuptake inhibitor paroxetine: Nonlinearity and relation to the sparteine oxidation polymorphism

1 reference

12 December 2020

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

1 reference

12 December 2020

MODFIT: a pharmacokinetics computer program

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00316471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8513845%20AND%20SRC:MED&resulttype=core&format=json

13 October 2019

1 reference