(Q61819217)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

review article

1 reference

title

Tumour necrosis factor and cancer (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Frances Balkwill

series ordinal

1

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language of work or name

English

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publication date

3 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

361-371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19343034%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrc2628

25 January 2020

exact match

0 references

cites work

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

The TNF and TNF receptor superfamilies: integrating mammalian biology

31 March 2020

1 reference

NF-kappaB functions as a tumour promoter in inflammation-associated cancer

31 March 2020

1 reference

TNF-alpha in promotion and progression of cancer

31 March 2020

1 reference

TNF: a master switch for inflammation to cancer

31 March 2020

1 reference

Development of anti-TNF therapy for rheumatoid arthritis

31 March 2020

1 reference

Infliximab maintenance therapy for fistulizing Crohn's disease

31 March 2020

1 reference

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

31 March 2020

1 reference

A phase II study of etanercept (Enbrel), a tumor necrosis factor alpha inhibitor in patients with metastatic breast cancer.

31 March 2020

1 reference

Study of etanercept, a tumor necrosis factor-alpha inhibitor, in recurrent ovarian cancer

31 March 2020

1 reference

Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose

31 March 2020

1 reference

A clinical study assessing the tolerability and biological effects of infliximab, a TNF-α inhibitor, in patients with advanced cancer

31 March 2020

1 reference

Tumor necrosis factor: renaissance as a cancer therapeutic?

31 March 2020

1 reference

II. Contribution to the Knowledge of Sarcoma

31 March 2020

1 reference

Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon

31 March 2020

1 reference

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

31 March 2020

1 reference

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

31 March 2020

1 reference

Molecular cloning and expression of human tumor necrosis factor and comparison with mouse tumor necrosis factor

31 March 2020

1 reference

Molecular cloning of mouse tumour necrosis factor cDNA and its eukaryotic expression

31 March 2020

1 reference

Use of monoclonal antibodies to a human cytotoxin for its isolation and for examining the self-induction of resistance to this protein

31 March 2020

1 reference

The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games

31 March 2020

1 reference

An APRIL to remember: novel TNF ligands as therapeutic targets

31 March 2020

1 reference

TNF family ligands define niches for T cell memory.

31 March 2020

1 reference

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

31 March 2020

1 reference

Molecular cloning and expression of a receptor for human tumor necrosis factor

31 March 2020

1 reference

A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins

31 March 2020

1 reference

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor

31 March 2020

1 reference

Many cytokines are very useful therapeutic targets in disease

31 March 2020

1 reference

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

31 March 2020

1 reference

In vivo anti-tumour activity of recombinant human and murine TNF, alone and in combination with murine IFN-gamma, on a syngeneic murine melanoma.

31 March 2020

1 reference

Tumor necrosis factor/cachectin-induced intravascular fibrin formation in meth A fibrosarcomas

31 March 2020

1 reference

Cytokines as communication signals between leukocytes and endothelial cells

31 March 2020

1 reference

The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors

31 March 2020

1 reference

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity

31 March 2020

1 reference

High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma

31 March 2020

1 reference

Synergistic effects of TNF-alpha and melphalan in an isolated limb perfusion model of rat sarcoma: a histopathological, immunohistochemical and electron microscopical study

31 March 2020

1 reference

TNF-alpha augments intratumoural concentrations of doxorubicin in TNF-alpha-based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects

31 March 2020

1 reference

Tumor necrosis factor alpha mediates homogeneous distribution of liposomes in murine melanoma that contributes to a better tumor response

31 March 2020

1 reference

Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

31 March 2020

1 reference

The effect of recombinant human tumour necrosis factor on growth and macromolecular synthesis of human epithelial cells

31 March 2020

1 reference

Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines

31 March 2020

1 reference

Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon

31 March 2020

1 reference

Crucial role of TNF-alpha in CD8 T cell-mediated elimination of 3LL-A9 Lewis lung carcinoma cells in vivo.

31 March 2020

1 reference

Compromised anti-tumor responses in tumor necrosis factor-alpha knockout mice

31 March 2020

1 reference

Tumour necrosis factor in man: clinical and biological observations

31 March 2020

1 reference

A phase I clinical trial of recombinant human tumor necrosis factor

31 March 2020

1 reference

Phase I study of recombinant human tumor necrosis factor

31 March 2020

1 reference

Isolated limb perfusion with melphalan and TNF-alpha in the treatment of extremity sarcoma

31 March 2020

1 reference

Outcome and prognostic factor analysis of 217 consecutive isolated limb perfusions with tumor necrosis factor-alpha and melphalan for limb-threatening soft tissue sarcoma

31 March 2020

1 reference

Coley's toxins in perspective.

31 March 2020

1 reference

Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line

31 March 2020

1 reference

Regulation of tumor necrosis factor gene expression in colorectal adenocarcinoma: in vivo analysis by in situ hybridization

31 March 2020

1 reference

In situ detection of tumour necrosis factor in human ovarian cancer specimens

31 March 2020

1 reference

Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression

31 March 2020

1 reference

Interleukin-6, tumour necrosis factor alpha and interleukin-1beta in patients with renal cell carcinoma

31 March 2020

1 reference

Tumour necrosis factor-alpha, interleukin-6, and fasting serum insulin correlate with clinical outcome in metastatic breast cancer patients treated with chemotherapy.

31 March 2020

1 reference

Tumor necrosis factor-alpha in the pathogenesis and treatment of cancer

31 March 2020

1 reference

Elevation of cytokine levels in cachectic patients with prostate carcinoma

31 March 2020

1 reference

Serum levels of IL-6 and TNF- correlate with clinicopathological features and patient survival in patients with prostate cancer

31 March 2020

1 reference

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo

31 March 2020

1 reference

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

31 March 2020

1 reference

Paradoxical effects of tumour necrosis factor in experimental ovarian cancer

31 March 2020

1 reference

Cells secreting tumour necrosis factor show enhanced metastasis in nude mice

31 March 2020

1 reference

Enhancement of experimental metastasis by tumor necrosis factor

31 March 2020

1 reference

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

31 March 2020

1 reference

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

31 March 2020

1 reference

Inflammation and cancer: back to Virchow?

31 March 2020

1 reference

Smoldering and polarized inflammation in the initiation and promotion of malignant disease

31 March 2020

1 reference

Cancer-related inflammation

31 March 2020

1 reference

The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells

31 March 2020

1 reference

Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis

31 March 2020

1 reference

Tumor necrosis factor-alpha promotes malignant pleural effusion

31 March 2020

1 reference

Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway.

31 March 2020

1 reference

Low levels of tumor necrosis factor alpha increase tumor growth by inducing an endothelial phenotype of monocytes recruited to the tumor site

31 March 2020

1 reference

Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK.

31 March 2020

1 reference

Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype

31 March 2020

1 reference

Expression and regulation of tumor necrosis factor alpha in normal and malignant ovarian epithelium

31 March 2020

1 reference

von Hippel-Lindau protein-mediated repression of tumor necrosis factor alpha translation revealed through use of cDNA arrays

31 March 2020

1 reference

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis.

31 March 2020

1 reference

Activated macrophages promote Wnt signalling through tumour necrosis factor-alpha in gastric tumour cells.

31 March 2020

1 reference

TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

31 March 2020

1 reference

Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation

31 March 2020

1 reference

Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis

31 March 2020

1 reference

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.

31 March 2020

1 reference

Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids

31 March 2020

1 reference

Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development

31 March 2020

1 reference

Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55

31 March 2020

1 reference

Regulatory T cells and treatment of cancer

31 March 2020

1 reference

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells.

31 March 2020

1 reference

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

31 March 2020

1 reference

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

31 March 2020

1 reference

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

31 March 2020

1 reference

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

31 March 2020

1 reference

Proinflammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc(Min/+) mice.

31 March 2020

1 reference

Infliximab chimeric antitumor necrosis factor-a monoclonal antibody as potential treatment for myelodysplastic syndromes.

31 March 2020

1 reference

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

31 March 2020

1 reference

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

31 March 2020

1 reference

IL-23 promotes tumour incidence and growth

31 March 2020

1 reference

New TNF-alpha releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen

31 March 2020

1 reference

Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials

31 March 2020

1 reference

Malignancy and biologic therapy in rheumatoid arthritis

31 March 2020

1 reference

TLRs, NLRs and RLRs: a trinity of pathogen sensors that co-operate in innate immunity

31 March 2020

1 reference

BCG immunotherapy of bladder cancer: 20 years on.

31 March 2020

1 reference

"Re-educating" tumor-associated macrophages by targeting NF-kappaB.

31 March 2020

1 reference

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

31 March 2020

1 reference

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

31 March 2020

1 reference

Adaptive immunity maintains occult cancer in an equilibrium state.

31 March 2020

1 reference

TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors

31 March 2020

1 reference

Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.

31 March 2020

1 reference

Single-chain TNF, a TNF derivative with enhanced stability and antitumoral activity

31 March 2020

1 reference

Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis

31 March 2020

1 reference

Tumor necrosis factor-alpha blocks apoptosis in melanoma cells when BRAF signaling is inhibited

31 March 2020

1 reference

Inhibitor of apoptosis proteins are regulated by tumour necrosis factor-alpha in malignant pleural mesothelioma

31 March 2020

1 reference

Tumor necrosis factor: an apoptosis JuNKie?

31 March 2020

1 reference

Signalling pathways of the TNF superfamily: a double-edged sword

31 March 2020

1 reference

Toll-like receptor signalling

31 March 2020

1 reference

Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system

31 March 2020

1 reference

Both lymphotoxin-alpha and TNF are crucial for control of Toxoplasma gondii in the central nervous system

31 March 2020

1 reference

Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor

31 March 2020

1 reference

Novel tumor necrosis factor-knockout mice that lack Peyer's patches

31 March 2020

1 reference

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

31 March 2020

1 reference

Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis

31 March 2020

1 reference

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

31 March 2020

1 reference

Anti-TNF antibody treatment of Crohn's disease

31 March 2020

1 reference

Etanercept in the treatment of psoriatic arthritis and psoriasis: a randomised trial

31 March 2020

1 reference

Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial

31 March 2020

1 reference

Evidence of a role of tumor necrosis factor alpha in refractory asthma.

31 March 2020

1 reference

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

31 March 2020

1 reference

Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein

31 March 2020

1 reference

31 March 2020

Inflammation and cancer

1 reference

Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells

31 March 2020

1 reference

12 December 2020

Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

1 reference

12 December 2020

Phase I study of recombinant tumor necrosis factor in cancer patients.

1 reference

12 December 2020

The treatment of malignant tumors by bacterial toxins as developed by the late William B. Coley, M.D., reviewed in the light of modern research.

1 reference

12 December 2020

Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization

1 reference

12 December 2020

The Treatment of Inoperable Sarcoma by Bacterial Toxins (the Mixed Toxins of the Streptococcus erysipelas and the Bacillus prodigiosus).

1 reference

12 December 2020

The role of tumor necrosis factor in health and disease.

1 reference

12 December 2020

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice

1 reference

12 December 2020

Serum levels of tumor necrosis factor-alpha and nutritional status in pancreatic cancer patients

1 reference

12 December 2020

Amplified expression of tumor necrosis factor receptor in cells transfected with Epstein-Barr virus shuttle vector cDNA libraries

1 reference

12 December 2020

Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation

1 reference

12 December 2020

Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer

1 reference

12 December 2020

Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice.

1 reference

12 December 2020

Characterization of the antitumor activities of human tumor necrosis factor-alpha and the comparison with other cytokines: induction of tumor-specific immunity

1 reference

12 December 2020

Rapid killing of actinomycin D-treated tumor cells by human mononuclear cells. I. Effectors belong to the monocyte-macrophage lineage.

1 reference

12 December 2020

Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells

1 reference

12 December 2020

Synergistic cytotoxic and antitumor effects of recombinant human tumor necrosis factor and hyperthermia

1 reference

12 December 2020

Human tumor xenografts treated with recombinant human tumor necrosis factor alone or in combination with interferons

1 reference

12 December 2020

Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors

1 reference

12 December 2020

Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein

1 reference

12 December 2020

A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity.

1 reference

12 December 2020

Immunomodulatory properties of recombinant murine and human tumor necrosis factor

1 reference

12 December 2020

An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors

1 reference

12 December 2020

The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia

1 reference

12 December 2020

Preparations of lymphotoxin induce resistance to their own cytotoxic effect

1 reference

12 December 2020

Human tumor necrosis factor. Production, purification, and characterization

1 reference

12 December 2020

Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

1 reference

12 December 2020

Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects.

1 reference

12 December 2020

The treatment of malignant tumors by repeated inoculations of erysipelas. With a report of ten original cases. 1893.

1 reference

12 December 2020

Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis

1 reference

12 December 2020

A review of the influence of bacterial infection and of bacterial products (Coley's toxins) on malignant tumors in man; a critical analysis of 30 inoperable cases treated by Coley's mixed toxins, in which diagnosis was confirmed by microscopic exam

1 reference

12 December 2020

Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats

1 reference

12 December 2020

Journal of the National Cancer Institute, Vol. 29, 1962: Action of bacterial polysaccharide on tumors. II. Damage of sarcoma 37 by serum of mice treated with Serratia marcescens polysaccharide, and induced tolerance.

1 reference

12 December 2020

Carcinogenic role of tumor necrosis factor-alpha inducing protein of Helicobacter pylori in human stomach

1 reference

12 December 2020

Lymphocyte in vitro cytotoxicity: mechanisms of immune and non-immune small lymphocyte mediated target L cell destruction

1 reference

12 December 2020

Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line

1 reference

12 December 2020