(Q65950306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

review article

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title

Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

N-Terminal Propeptide of Type III Collagen

25 April 2020

part of the series

Gene Wiki Review Series

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main subject

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1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

Gerard Tromp

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

author name string

Gerard Tromp

series ordinal

2

1 reference

http://europepmc.org/abstract/MED/31075413

26 July 2019

language of work or name

English

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publication date

7 May 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

volume

707

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

page(s)

151-171

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31075413%20AND%20SRC:MED&resulttype=core&format=json

Collagen Types and Anticollagen-Antibodies in Dupuytren's Disease

25 April 2020

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Platelet-collagen interaction : Adhesion of human blood platelets to purified (CB4) peptide from type III collagen

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Value of111indium chloride bone marrow scanning in the differential diagnosis of blood count depression in lymphoma

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Inheritance of Ehlers-Danlos type IV syndrome

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Amino acid sequence to the N-terminal non-triple helical cross link region of type III collagen

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Patients with Ehlers-Danlos syndrome type IV lack type III collagen

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Comparative investigation on the influence of human bovine collagen types I, II and III on the aggregation of human platelets

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A single base mutation in the gene for type III collagen (COL3A1) converts glycine 847 to glutamic acid in a family with Ehlers-Danlos syndrome type IV. An unaffected family member is mosaic for the mutation

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Substitution of aspartate for glycine 1018 in the type III procollagen (COL3A1) gene causes type IV Ehlers-Danlos syndrome: the mutated allele is present in most blood leukocytes of the asymptomatic and mosaic mother.

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A 15 base-pair AT-rich variable number tandem repeat in the type III procollagen gene (COL3A1) as an informative marker for 2q31-2q32.3

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Increased serum concentration of type IV collagen peptide and type III collagen peptide in hyperthyroidism

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Increased collagen type III synthesis by fibroblasts isolated from strictures of patients with Crohn's disease

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12 December 2020

Detection and characterisation of an overmodified type III collagen by analysis of non-cutaneous connective tissues in a patient with Ehlers-Danlos syndrome IV

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12 December 2020

Human bone contains type III collagen, type VI collagen, and fibrillin: type III collagen is present on specific fibers that may mediate attachment of tendons, ligaments, and periosteum to calcified bone cortex

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Characterization of a large deletion associated with a polymorphic block of repeated dinucleotides in the type III procollagen gene (COL3A1) of a patient with Ehlers-Danlos syndrome type IV.

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Dermal collagen fibrils are hybrids of type I and type III collagen molecules.

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A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms

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12 December 2020

Inheritance of an RNA splicing mutation (G+ 1 IVS20) in the type III procollagen gene (COL3A1) in a family having aortic aneurysms and easy bruisability: phenotypic overlap between familial arterial aneurysms and Ehlers-Danlos syndrome type IV.

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12 December 2020

Identical G+1 to A mutations in three different introns of the type III procollagen gene (COL3A1) produce different patterns of RNA splicing in three variants of Ehlers-Danlos syndrome. IV. An explanation for exon skipping some mutations and not othe

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12 December 2020

A single base mutation that substitutes serine for glycine 790 of the alpha 1 (III) chain of type III procollagen exposes an arginine and causes Ehlers-Danlos syndrome IV

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12 December 2020

Isolation of cDNA and genomic clones encoding human pro-alpha 1 (III) collagen. Partial characterization of the 3' end region of the gene

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12 December 2020

Construction of a human pro alpha 1(III) collagen cDNA clone and localization of type III collagen expression in human fetal tissues

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12 December 2020

Structure of cDNA clones coding for the entire prepro alpha 1 (III) chain of human type III procollagen. Differences in protein structure from type I procollagen and conservation of codon preferences

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12 December 2020

Nucleotide and amino acid sequences of the entire human alpha 1 (III) collagen

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12 December 2020

Single base mutation in the type III procollagen gene that converts the codon for glycine 883 to aspartate in a mild variant of Ehlers-Danlos syndrome IV.

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12 December 2020

Ehlers-Danlos syndrome type IV: a multi-exon deletion in one of the two COL3A1 alleles affecting structure, stability, and processing of type III procollagen

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12 December 2020

Isolation and characterization of collagen in Peyronie's disease

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12 December 2020

Synthesis of an altered type III procollagen in a patient with type IV Ehlers-Danlos syndrome. A structural change in the alpha 1(III) chain which makes the protein more susceptible to proteinases

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12 December 2020

Human pro α 1(III) collagen: cDNA sequence for the 3′ end

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12 December 2020

Rapid equilibrium radioimmunoassay for the amino-terminal propeptide of human type III procollagen

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12 December 2020

Nucleotide sequence of a cDNA coding for the amino-terminal region of human prepro α1(III) collagen

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12 December 2020

Complete nucleotide sequence of the N-terminal domains of the murine alpha-1 type-III collagen chain

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12 December 2020

Aminoterminal propeptide of type III procollagen in healing wound in humans

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12 December 2020

Human type III collagen gene expression is coordinately modulated with the type I collagen genes during fibroblast growth.

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12 December 2020

Type III collagen aminopropeptide levels in serum of patients with progressive systemic scleroderma

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12 December 2020

Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts

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12 December 2020

Identification of three genetically distinct collagens by cyanogen bromide cleavage of insoluble human skin and cartilage collagen

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12 December 2020

Distribution of laminin, fibronectin, and interstitial collagen type III in soft tissue tumours

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12 December 2020

Molecular cloning and carboxyl-propeptide analysis of human type III procollagen

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12 December 2020

Heritable diseases of collagen

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12 December 2020

Altered secretion of type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts

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12 December 2020

Complete amino acid sequence of the N-terminal extension of calf skin type III procollagen

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12 December 2020

Collagen fibrillogenesis in vitro: comparison of types I, II, and III.

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12 December 2020

Serum type III procollagen peptide concentration in cryptogenic fibrosing alveolitis and its clinical relevance

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12 December 2020

A uniquely conserved regulatory signal is found around the translation initiation site in three different collagen genes.

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12 December 2020

Covalent structure of collagen: amino acid sequence of alpha 1(III)-CB9 from type III collagen of human liver

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12 December 2020

Folding mechanism of the triple helix in type-III collagen and type-III pN-collagen. Role of disulfide bridges and peptide bond isomerization

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12 December 2020

Collagens: molecular biology, diseases, and potentials for therapy

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12 December 2020

Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage

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12 December 2020

Dilated cardiomyopathy is associated with an increase in the type I/type III collagen ratio: a quantitative assessment

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12 December 2020

The mouse type-III procollagen-encoding gene: genomic cloning and complete DNA sequence.

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12 December 2020

Type III collagen in normal human articular cartilage

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12 December 2020

Single base mutation that substitutes glutamic acid for glycine 1021 in the COL3A1 gene and causes Ehlers-Danlos syndrome type IV

1 reference

12 December 2020

Collagen-platelet interaction: separate receptor sites for types I and III collagen

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12 December 2020

Exclusion of mutations in the gene for type III collagen (COL3A1) as a common cause of intracranial aneurysms or cervical artery dissections: results from sequence analysis of the coding sequences of type III collagen from 55 unrelated patients

1 reference

12 December 2020

Parental somatic and germ-line mosaicism for a multiexon deletion with unusual endpoints in a type III collagen (COL3A1) allele produces Ehlers-Danlos syndrome type IV in the heterozygous offspring

1 reference

12 December 2020

Temperature sensitivity of aberrant RNA splicing with a mutation in theG+5 position of intron 37 of the gene for type III procollagen from a patient with Ehlers-Danlos syndrome type IV

1 reference

12 December 2020

Sequencing of cDNA from 50 unrelated patients reveals that mutations in the triple-helical domain of type III procollagen are an infrequent cause of aortic aneurysms

1 reference

12 December 2020

Biosynthesis of recombinant human pro-alpha 1(III) chains in a baculovirus expression system: production of disulphide-bonded and non-disulphide-bonded species containing full-length triple helices

1 reference

12 December 2020

Characterization of human type III collagen expressed in a baculovirus system. Production of a protein with a stable triple helix requires coexpression with the two types of recombinant prolyl 4-hydroxylase subunit

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12 December 2020

Coordinate patterns of expression of type I and III collagens during mouse development.

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12 December 2020

Synthesis of type III collagen and type IV collagen by tubular epithelial cells in diabetic nephropathy

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12 December 2020

COL3A1 mutations cause variable clinical phenotypes including acrogeria and vascular rupture

1 reference

12 December 2020

Multiple Defects in Type III Collagen Synthesis Are Associated with the Pathogenesis of Abdominal Aortic Aneurysms

1 reference

12 December 2020

A glycine (415)-to-serine substitution results in impaired secretion and decreased thermal stability of type III procollagen in a patient with Ehlers-Danlos syndrome type IV

1 reference

12 December 2020

Mutations in the COL3A1 gene result in the Ehlers-Danlos syndrome type IV and alterations in the size and distribution of the major collagen fibrils of the dermis

1 reference

12 December 2020

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

1 reference

12 December 2020

Mutations in fibrillar collagens (types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of diseases of bone, cartilage, and blood vessels

1 reference

12 December 2020

Urinary and serum type III collagen: markers of renal fibrosis

1 reference

12 December 2020

Assembly of human prolyl 4-hydroxylase and type III collagen in the yeast pichia pastoris: formation of a stable enzyme tetramer requires coexpression with collagen and assembly of a stable collagen requires coexpression with prolyl 4-hydroxylase

1 reference

12 December 2020

Splicing defects in the COL3A1 gene: marked preference for 5' (donor) spice-site mutations in patients with exon-skipping mutations and Ehlers-Danlos syndrome type IV.

1 reference

12 December 2020

Synthesis and conformational properties of a recombinant C-propeptide of human type III procollagen

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12 December 2020

Collagen subtypes and matrix metalloproteinase in idiopathic restrictive cardiomyopathy.

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12 December 2020

Aberrant type I and type III collagen gene expression in human breast cancer in vivo

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12 December 2020

The role of type III collagen in the development of familial abdominal aortic aneurysms

1 reference

12 December 2020

A new platelet receptor specific to type III collagen. Type III collagen-binding protein

1 reference

12 December 2020

Characterization of 11 new mutations in COL3A1 of individuals with Ehlers-Danlos syndrome type IV: preliminary comparison of RNase cleavage, EMC and DHPLC assays

1 reference

12 December 2020

Collagen remodeling and cardiac dysfunction in patients with hypertrophic cardiomyopathy: the significance of type III and VI collagens

1 reference

12 December 2020

Genomic organization of the human COL3A1 and COL5A2 genes: COL5A2 has evolved differently than the other minor fibrillar collagen genes

1 reference

12 December 2020

Structure of type I and type III heterotypic collagen fibrils: an X-ray diffraction study

1 reference

12 December 2020

Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease

1 reference

12 December 2020

The design, execution, and interpretation of genetic association studies to decipher complex diseases.

1 reference

12 December 2020

Neurological presentation of Ehlers-Danlos syndrome type IV in a family with parental mosaicism

1 reference

12 December 2020

Structure formation in the C terminus of type III collagen guides disulfide cross-linking.

1 reference

12 December 2020

Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13

1 reference

12 December 2020

RNA-binding proteins heterogeneous nuclear ribonucleoprotein A1, E1, and K are involved in post-transcriptional control of collagen I and III synthesis.

1 reference

12 December 2020

Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms

1 reference

12 December 2020

A novel binding site in collagen type III for integrins alpha1beta1 and alpha2beta1

1 reference

12 December 2020

Functional changes in bladder tissue from type III collagen-deficient mice.

1 reference

12 December 2020

Interstitial fibrosis in the heart: differences in extracellular matrix proteins and matrix metalloproteinases in end-stage dilated, ischaemic and valvular cardiomyopathy

1 reference

12 December 2020

Aortic stiffness correlates with an increased extracellular matrix turnover in patients with dilated cardiomyopathy

1 reference

12 December 2020

Clinical and echocardiographic correlates of plasma procollagen type III amino-terminal peptide levels in the community

1 reference

12 December 2020

Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy

1 reference

12 December 2020

Biochemical characterization of genetic mutations of GPR56 in patients with bilateral frontoparietal polymicrogyria (BFPP).

1 reference

12 December 2020

Natural variation in four human collagen genes across an ethnically diverse population

1 reference

12 December 2020

Identification of a major GpVI-binding locus in human type III collagen

1 reference

12 December 2020

Crystal structure of human type III collagen Gly991-Gly1032 cystine knot-containing peptide shows both 7/2 and 10/3 triple helical symmetries

1 reference

12 December 2020

Homozygosity for a null allele of COL3A1 results in recessive Ehlers-Danlos syndrome

1 reference

12 December 2020

A novel point mutation at donor splice-site in intron 42 of type III collagen gene resulting in the inclusion of 30 nucleotides into the mature mRNA in a case of vascular type of Ehlers-Danlos syndrome

1 reference

12 December 2020

Hypoxia-inducible factor 1alpha inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III

1 reference

12 December 2020

Location of 3-hydroxyproline residues in collagen types I, II, III, and V/XI implies a role in fibril supramolecular assembly

1 reference

12 December 2020

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen

1 reference

12 December 2020

Type III collagen, a fibril network modifier in articular cartilage

1 reference

12 December 2020

The haploinsufficient Col3a1 mouse as a model for vascular Ehlers-Danlos syndrome.

1 reference

12 December 2020

The origin of fibroblasts and mechanism of cardiac fibrosis

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12 December 2020

Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial.

1 reference

12 December 2020

Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers-Danlos syndrome

1 reference

12 December 2020

Genes and abdominal aortic aneurysm

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12 December 2020

Nerve growth factor induces type III collagen production in chronic allergic airway inflammation.

1 reference

12 December 2020

Loss of Col3a1, the gene for Ehlers-Danlos syndrome type IV, results in neocortical dyslamination

1 reference

12 December 2020

Unipro UGENE: a unified bioinformatics toolkit

1 reference

12 December 2020

Usefulness of circulating biomarkers for the prediction of left ventricular remodeling after myocardial infarction

1 reference

12 December 2020

Chronic treatment with a broad-spectrum metalloproteinase inhibitor, doxycycline, prevents the development of spontaneous aortic lesions in a mouse model of vascular Ehlers-Danlos syndrome.

1 reference

12 December 2020

Structural basis of fibrillar collagen trimerization and related genetic disorders

1 reference

12 December 2020

The relationship between markers of extracellular cardiac matrix turnover: infarct healing and left ventricular remodelling following primary PCI in patients with first-time STEMI.

1 reference

12 December 2020

Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics

1 reference

12 December 2020

Type III collagen regulates osteoblastogenesis and the quantity of trabecular bone

1 reference

12 December 2020

Variants of COL3A1 are associated with the risk of stroke recurrence and prognosis in the Chinese population: a prospective study

1 reference

12 December 2020

Survival is affected by mutation type and molecular mechanism in vascular Ehlers-Danlos syndrome (EDS type IV).

1 reference

12 December 2020

1 reference

12 December 2020

Molecular basis and genetic predisposition to intracranial aneurysm

1 reference

12 December 2020

Vascular Ehlers-Danlos Syndrome in siblings with biallelic COL3A1 sequence variants and marked clinical variability in the extended family

1 reference

12 December 2020

The Tsk2/+ mouse fibrotic phenotype is due to a gain-of-function mutation in the PIIINP segment of the Col3a1 gene

1 reference

12 December 2020

A comparative encyclopedia of DNA elements in the mouse genome

1 reference

12 December 2020

Type III collagen modulates fracture callus bone formation and early remodeling

1 reference

12 December 2020

Urine Collagen Fragments and CKD Progression-The Cardiovascular Health Study

1 reference

12 December 2020

The type of variants at the COL3A1 gene associates with the phenotype and severity of vascular Ehlers-Danlos syndrome

1 reference

12 December 2020

Clinical, structural, biochemical and X-ray crystallographic correlates of pathogenicity for variants in the C-propeptide region of the COL3A1 gene.

1 reference

12 December 2020

Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis

1 reference

12 December 2020

Understanding the pathogenesis of abdominal aortic aneurysms

1 reference

12 December 2020

New frontiers in fibrotic disease therapies: The focus of the Joan and Joel Rosenbloom Center for Fibrotic Diseases at Thomas Jefferson University

1 reference

12 December 2020

The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis.

1 reference

12 December 2020

Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.

1 reference

12 December 2020

Arterial complications of vascular Ehlers-Danlos syndrome

1 reference

12 December 2020

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

1 reference

12 December 2020

Noninvasive markers of liver fibrosis: on-treatment changes of serum markers predict the outcome of antifibrotic therapy

1 reference

12 December 2020

Development of a Novel Enzyme-Linked Immunosorbent Assay Targeting a Neo-Epitope Generated by Cathepsin-Mediated Turnover of Type III Collagen and Its Application in Chronic Obstructive Pulmonary Disease

1 reference

12 December 2020

Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review.

1 reference

12 December 2020

Bi-allelic variants in COL3A1 encoding the ligand to GPR56 are associated with cobblestone-like cortical malformation, white matter changes and cerebellar cysts

1 reference

12 December 2020

Diagnosis, natural history, and management in vascular Ehlers-Danlos syndrome.

1 reference

12 December 2020

The 2017 international classification of the Ehlers-Danlos syndromes

1 reference

12 December 2020

Misbalance in type III collagen formation/degradation as a novel serological biomarker for penetrating (Montreal B3) Crohn's disease.

1 reference

12 December 2020

AJKD Atlas of Renal Pathology: Type III Collagen Glomerulopathy.

1 reference

12 December 2020

Hydroxylation of Human Type III Collagen Alpha Chain by Recombinant Coexpression with a Viral Prolyl 4-Hydroxylase in Escherichia coli

1 reference

12 December 2020

The good and the bad collagens of fibrosis - Their role in signaling and organ function

1 reference

12 December 2020

Biallelic COL3A1 mutations result in a clinical spectrum of specific structural brain anomalies and connective tissue abnormalities.

1 reference

12 December 2020

Fibroblasts and the extracellular matrix in right ventricular disease.

1 reference

12 December 2020

Overexpression of COL3A1 confers a poor prognosis in human bladder cancer identified by co-expression analysis

1 reference

12 December 2020

Exogenous growth factors enhance the expression of cola1, cola3, and Elastin in fibroblasts via activating MAPK signaling pathway.

1 reference

12 December 2020

Branched-chain amino acids regulate type I tropocollagen and type III tropocollagen syntheses via modulation of mTOR in the skin.

1 reference

12 December 2020

Proteasome-mediated degradation of collagen III by cortisol in amnion fibroblasts.

1 reference

12 December 2020

Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome.

1 reference

12 December 2020

Overexpression of LncRNA AC067945.2 Down-Regulates Collagen Expression in Skin Fibroblasts and Possibly Correlates with the VEGF and Wnt Signalling Pathways.

1 reference

12 December 2020

Molecular and tissue alterations of collagens in fibrosis.

1 reference

12 December 2020

A Variant of COL3A1 (rs3134646) Is Associated With Risk of Developing Diverticulosis in White Men.

1 reference

12 December 2020

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model.

1 reference

12 December 2020

Hypoxia induces endothelial‑mesenchymal transition in pulmonary vascular remodeling.

1 reference

12 December 2020

Vascular aspects of the Ehlers-Danlos Syndromes

1 reference

12 December 2020

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension

1 reference

12 December 2020

High turnover of extracellular matrix reflected by specific protein fragments measured in serum is associated with poor outcomes in two metastatic breast cancer cohorts

1 reference

12 December 2020

The Effects of Adipose Stem Cell-Conditioned Media on Fibrogenesis of Dermal Fibroblasts Stimulated by Transforming Growth Factor-β1

1 reference

12 December 2020

Knockdown of collagen α-1(III) inhibits glioma cell proliferation and migration and is regulated by miR128-3p

1 reference

12 December 2020

European multicentre study validates enhanced liver fibrosis test as biomarker of fibrosis in systemic sclerosis

1 reference

12 December 2020

A cysteine-based molecular code informs collagen C-propeptide assembly

1 reference

12 December 2020