(Q68320677)

English

Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI)

scientific article published on April 15, 1988

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23 September 2019

Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI) (English)

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23 September 2019

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31 December 2022

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31 December 2022

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31 December 2022

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P. Dayer

1

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31 December 2022

J. Desmeules

2

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T. Leemann

3

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R. Striberni

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1 April 1988

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15 April 1988

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National Center for Biotechnology Information

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Biochemical and Biophysical Research Communications

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23 September 2019

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23 September 2019

411-416

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23 September 2019

1

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23 September 2019

Polymorphic hydroxylation of Debrisoquine in man.

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7 January 2021

Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Evidence for an enzymatic defect in the 4-hydroxylation of debrisoquine by human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Characterization of a common genetic defect of cytochrome P-450 function (debrisoquine-sparteine type polymorphism)--increased Michaelis is Constant (Km) and loss of stereoselectivity of bufuralol 1'-hydroxylation in poor metabolizers

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Genetically determined variability in acetylation and oxidation. Therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Single-dose quinidine treatment inhibits metoprolol oxidation in extensive metabolizers

1 reference

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7 January 2021

Competitive inhibition of sparteine oxidation in human liver by β-adrenoceptor antagonists and other cardiovascular drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2888%2980729-0

7 January 2021

Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes.

1 reference

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7 January 2021

Protein measurement with the Folin phenol reagent

16

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10.1016/S0006-291X(88)80729-0

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31 December 2022

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10.1016/S0006-291X(88)80729-0

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Europe PubMed Central

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23 September 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3358767%20AND%20SRC:MED&resulttype=core&format=json

23 September 2019

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