(Q70535295)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8422689%20AND%20SRC:MED&resulttype=core&format=json

12 October 2019

title

Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma (English)

1 reference

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12 October 2019

1 reference

G J Peters

1

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12 October 2019

J Lankelma

2

1 reference

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12 October 2019

R M Kok

3

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12 October 2019

P Noordhuis

4

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12 October 2019

C J van Groeningen

5

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12 October 2019

C L van der Wilt

6

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12 October 2019

S Meyer

7

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12 October 2019

H M Pinedo

8

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12 October 2019

publication date

1 January 1993

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Cancer Chemotherapy and Pharmacology

12 October 2019

published in

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12 October 2019

volume

31

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12 October 2019

page(s)

269-276

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12 October 2019

issue

4

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https://scigraph.springernature.com/pub.10.1007/bf00685670

12 October 2019

exact match

0 references

cites work

In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil

1 reference

12 December 2020

Kinetic modeling of in vivo--nuclear magnetic resonance spectroscopy data: 5-fluorouracil in liver and liver tumors

1 reference

12 December 2020

Clinical pharmacology of 5-fluorouracil

1 reference

12 December 2020

Prediction of 5-fluorouracil cytotoxicity towards the Walker carcinosarcoma using peak integrals of fluoronucleotides measured by MRS in vivo

1 reference

12 December 2020

Pharmacokinetics of 5-fluorouracil infusions in the rat: comparison with man and other species

1 reference

12 December 2020

The analysis of 5-fluorouracil in human plasma by gas chromatography-negative ion chemical ionization mass spectrometry (GC-NICIMS) with stable isotope dilution

1 reference

12 December 2020

Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule

1 reference

12 December 2020

pH dependence of 5-fluorouracil uptake observed by in vivo 31P and 19F nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

Tissue homogenization using a micro-dismembrator for the measurement of enzyme activities

1 reference

12 December 2020

The relationship between plasma pharmacokinetics and tissue metabolites of 5-fluorouracil (5-FU) in patients with colorectal cancer

1 reference

12 December 2020

Active Transport of 5-Fluorouracil and Its Energy Coupling in Ehrlich Ascites Tumor Cells1

1 reference

12 December 2020

Distribution of 18F-5-Fluorouracil in tumor-bearing mice and rats

1 reference

12 December 2020

Metabolites of 5-fluorouracil in plasma and urine, as monitored by 19F nuclear magnetic resonance spectroscopy, for patients receiving chemotherapy with or without methotrexate pretreatment

1 reference

12 December 2020

Modulation of 5-fluorouracil toxicity by uridine, deoxyuridine, orotate and dipyridamole in normal tissues of rats with liver adenocarcinoma

1 reference

12 December 2020

Measurement of in vitro cellular pharmacokinetics of 5-fluorouracil in human and rat cancer cell lines and rat hepatocytes using a flow-through system

1 reference

12 December 2020

5-fluorouracil metabolism monitored in vivo by 19F NMR.

1 reference

12 December 2020

The influence of drug interval on the effect of methotrexate and fluorouracil in the treatment of advanced colorectal cancer

1 reference

12 December 2020

Tumor trapping of 5-fluorouracil: in vivo 19F NMR spectroscopic pharmacokinetics in tumor-bearing humans and rabbits

1 reference

12 December 2020

Real-time follow-up of 5-fluorouracil metabolism in the liver of tumor patients by means of F-19 MR spectroscopy

1 reference

12 December 2020

Intestinal 5-fluorouracil absorption: use of Ussing chambers to assess transport and metabolism

1 reference

12 December 2020

Facilitated transport of uracil and 5-fluorouracil, and permeation of orotic acid into cultured mammalian cells

1 reference

12 December 2020

A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa

1 reference

12 December 2020

5-Fluorouracil radiation sensitization--a brief review

1 reference

12 December 2020

Highly sensitive determination of 5-fluorouracil in human plasma by capillary gas chromatography and negative ion chemical ionization mass spectrometry

1 reference

12 December 2020

Correlation of 5-fluorouracil (NSC-19893) distribution in rodents with toxicity and chemotherapy in man

1 reference

12 December 2020

5-Fluorouracil substitution alters pre-mRNA splicing in vitro

1 reference

12 December 2020

Pharmacokinetic studies of anticancer drugs in tumor-bearing animals.

1 reference

12 December 2020

Determination of 5-fluorouracil (NSC-19893) plasma levels in rats and man by isotope dilution-mass fragmentography

1 reference

12 December 2020

Non-linear pharmacokinetics of 5-fluorouracil as described by in vivo behaviour of 5,6 dihydro-5-fluorouracil

1 reference

12 December 2020

Diurnal variation in the therapeutic efficacy of 5-fluorouracil against murine colon cancer

1 reference

12 December 2020

Elevation of thymidylate synthase following 5-fluorouracil treatment is prevented by the addition of leucovorin in murine colon tumors

1 reference

12 December 2020

Tissue distribution of [18F]-5-fluorouracil in mice: effects of route of administration, strain, tumour and dose

1 reference

12 December 2020

Thymidylate synthetase - a target enzyme in cancer chemotherapy

1 reference

12 December 2020

Clinical relevance of biochemical modulation of 5-fluorouracil

1 reference

12 December 2020

Fluorouracil: biochemistry and pharmacology

1 reference

12 December 2020

Increased levels of DNA lesions induced by leucovorin-5-fluoropyrimidine in human colon adenocarcinoma

1 reference

12 December 2020

Schedule-dependent enhancement of the cytotoxicity of fluoropyrimidines to human carcinoma cells in the presence of folinic acid

1 reference

12 December 2020

Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites

1 reference

12 December 2020

The application of nuclear magnetic resonance spectroscopy to drug metabolism studies

1 reference

12 December 2020

Effect of Leucovorin on 5-Fluorouracil Induced Inhibition of Thymidylate Synthase in Patients with Colon Cancer

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00685670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8422689%20AND%20SRC:MED&resulttype=core&format=json

12 October 2019

1 reference