(Q72495549)

English

In kitten ventricular myocardium, the inotropic potency of an agonist is determined by both its intrinsic activity for the adenylyl cyclase and its affinity for the beta-adrenoceptors

scientific article published on 01 August 1981

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scholarly article

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Europe PubMed Central

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27 October 2019

In kitten ventricular myocardium, the inotropic potency of an agonist is determined by both its intrinsic activity for the adenylyl cyclase and its affinity for the beta-adrenoceptors (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6116196%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

author name string

A J Kaumann

1

1 reference

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27 October 2019

publication date

1 August 1981

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27 October 2019

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

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27 October 2019

317

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27 October 2019

13-18

1 reference

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27 October 2019

1

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27 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00506250

0 references

High efficiency coupling between beta-adrenergic receptors and cardiac contractility: direct evidence for "spare" beta-adrenergic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of the effects of isoprenaline and noradrenaline by hydrocortisone in cat heart muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation by adrenaline and dopamine but not by noradrenaline of myocardial ?-adrenoceptors mediating positive inotropic effects in human atrial preparations

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Adrenoceptor blocking agents as partial agonists in isolated heart muscle: dissociation of stimulation and blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that (+)-bupranolol interacts directly with myocardial beta-adrenoceptors. Control of optical purity with differential thermal analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of beta-adrenergic receptors by guanyl-5'-yl imidodiphosphate and other purine nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convenient apparatus for recording contractions of isolated heart muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On spare ?-adrenoceptors for inotropic effects of catecholamines in kitten ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective activation of particulate cAMP-dependent protein kinase by isoproterenol and prostaglandin E1

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative assessment of?-adrenoceptor blocking agents as simple competitive antagonists in isolated heart muscle: Similarity of inotropic and chronotropic blocking potencies against isoproterenol

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adrenergic receptors in heart muscle: relations among factors influencing the sensitivity of the cat papillary muscle to catecholamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxation of heart muscle by catecholamines and by dibutyryl cyclic adenosine 3',5'-monophosphate. Similarity of beta-adrenoceptors mediating contractile and relaxant effects of catecholamines in kitten pipillary muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple effects of guanosine triphosphate on beta adrenergic receptors and adenylate cyclase activity in rat heart, lung and brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the influence of N-isopropyl and N-tert butyl substituents on the affinity of ligands for sinoatrial ?-adrenoceptors in rat atria and ?-adrenoceptors coupled to the adenylyl cyclase in kitten ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

125IIodohydroxybenzylpindolol binding sites on intact rat glioma cells. Evidence for beta-adrenergic receptors of high coupling efficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly sensitive adenylate cyclase assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Affinity and intrinsic activity in the theory of competitive inhibition. I. Problems and theory

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of kitten atria to chronotropic, inotropic and adenylyl cyclase stimulating effects of (-)isoprenaline

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the presence and distribution of ?-adrenoceptors in the heart of various mammalian species

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on receptor-mediated activation of adenylyl cyclases. IV. Characteristics of the adrenergic receptor coupled to myocardial adenylyl cyclase: stereospecificity for ligands and determination of apparent affinity constants for beta-blockers

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iodohydroxybenzylpindolol: preparation, purification, localization of its iodine to the indole ring, and characterization as a partial agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin E1 action on sinus pacemaker and adenylyl cyclase in kitten myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of myocardial ?-adrenoceptors by the nitrogen-free low affinity ligand 3?,4?-dihydroxy-?-methylpropiophenone (U-0521)

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A modification of receptor theory

1 reference

https://pubmed.ncbi.nlm.nih.gov/6116196

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00506250

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6116196%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:6116196%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

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