(Q73241292)

English

Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue

scientific article published on 01 April 1997

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scholarly article

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2 November 2019

Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue (English)

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2 November 2019

author name string

D A Cross

1

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2 November 2019

P W Watt

2

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2 November 2019

M Shaw

3

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2 November 2019

J van der Kaay

4

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2 November 2019

C P Downes

5

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2 November 2019

J C Holder

6

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2 November 2019

P Cohen

7

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2 November 2019

publication date

1 April 1997

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2 November 2019

1 reference

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2 November 2019

406

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2 November 2019

211-215

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2 November 2019

1-2

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2 November 2019

Glycogen Synthase from Rabbit Skeletal Muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

The protein phosphatases involved in cellular regulation. Purification and characterisation of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Regulation of protein phosphatase-1G from rabbit skeletal muscle. 2. Catalytic subunit translocation is a mechanism for reversible inhibition of activity toward glycogen-bound substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Insulin stimulation of mitogen-activated protein kinase, p90rsk, and p70 S6 kinase in skeletal muscle of normal and insulin-resistant mice. Implications for the regulation of glycogen synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositolphospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Evidence for communication between nerve growth factor and protein tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

The purification and properties of rabbit skeletal muscle glycogen synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900240-8

7 January 2021

Identifiers

10.1016/S0014-5793(97)00240-8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9109420%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9109420%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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